Year 2022

• Microscopic and Spectroscopic Imaging and Thermal Analysis of Acrylates, Silicones and Active Pharmaceutical Ingredients in Adhesive Transdermal Patches

  Publication

  • M. Jamrógiewicz
  • B. Mikolaszek
  • K. Pieńkowska
  • M. Sznitowska

  - Polymers - Year 2022

  Dermal or transdermal patches are increasingly becoming a noteworthy alternative ascarriers for active pharmaceutical ingredients (APIs), which makes their detailed physicochemical evaluation essential for pharmaceutical development. This paper demonstrates mid-infrared (FTIR) and Raman spectroscopy with complementary microscopic methods (SEM, optical and confocal Raman microscopy) and differential scanning calorimetry...

Year 2021

• PLA–Potato Thermoplastic Starch Filament as a Sustainable Alternative to the Conventional PLA Filament: Processing, Characterization, and FFF 3D Printing

  Publication

  • A. Haryńska
  • H. Janik
  • M. Sienkiewicz
  • B. Mikolaszek
  • J. Kucińska-Lipka

  - ACS Sustainable Chemistry & Engineering - Year 2021

  The growing popularity of the fused filament fabrication (FFF) 3D printing technology in science, industry, and in-home use is associated with an increased demand for high-quality polymer filaments. This study presents an in-depth characterization and analysis of a self-made bio-based polylactide (PLA)/thermoplastic potato starch (TPS) filament dedicated for the FFF 3D printing technology. The obtained results were compared with...

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• Spectroscopic evaluation on pseudopolymorphs of sodium naproxen

  Publication

  • M. Jamrógiewicz
  • K. Milewska
  • B. Mikolaszek

  - SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY - Year 2021

  This paper demonstrates the assessment of vibrational spectroscopy methods such as middle infrared, near infrared and Raman spectroscopy (FTIR, FT-NIR, Raman) for the identification of pseudopolymorphic forms of a model active pharmaceutical ingredient (API) - sodium naproxen (NpxNa). NpxNa, in the form of three different pseudopolymorphs, was investigated by methods dedicated for solid state characterization: DSC (differential...

Year 2016

• Physical and Mechanical Evaluation of Silicone-Based Double-Layer Adhesive Patch Intended for Keloids and Scar Treatment Therapy

  Publication

  • M. Jamrógiewicz
  • B. Mikolaszek
  • K. Pieńkowska
  • M. Żebrowska
  • M. Sznitowska
  • J. Strankowska

  - Polymers - Year 2016

  Growing interest in silicone elastomers for pharmaceutical purposes is due to both theirbeneficial material effect for scar treatment and their potential as drug carriers. Regarding their morphological structure, silicone polymers possess unique properties, which enable a wide range of applicability possibilities. The present study focused on developing a double-layer adhesive silicone film (DLASil) by evaluating its physical...

Year 2015

• Double layer adhesive silicone dressing as a potential dermal drug delivery film in scar treatment

  Publication

  • M. Jamrógiewicz
  • K. Pieńkowska
  • M. Żebrowska
  • B. Mikolaszek
  • M. Sznitowska

  - International Journal of Pharmaceutics: X - Year 2015

  The present studies focused on the evaluation of design of an adhesive silicone film intended for scar treatment. Developed silicone double layer film was examined in terms of its future relevance to therapy and applicability on the human skin considering properties which included in vitro permeability of water vapor and oxygen. In order to adapt the patches for medical use in the future there were tested such properties as...