Karol Jacek - Publications - Bridge of Knowledge

Karol Jacek

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Year 2021

Hydration of Simple Model Peptides in Aqueous Osmolyte Solutions
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- INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - Year 2021
The biology and chemistry of proteins and peptides are inextricably linked with water as the solvent. The reason for the high stability of some proteins or uncontrolled aggregation of others may be hidden in the properties of their hydration water. In this study, we investigated the effect of stabilizing osmolyte–TMAO (trimethylamine N-oxide) and destabilizing osmolyte–urea on hydration shells of two short peptides, NAGMA (N-acetyl-glycine-methylamide)...

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