Year 2008

• The organophosphorus sulfenyl bromides as versatile reagents for cysteine derivatives functionalization by unsymmetrical disulfide bond formation

  Publication

  • M. Szymelfejnik
  • S. Demkowicz
  • D. Witt
  • J. Rachoń

  - PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS - Year 2008

  We have developed a convenient method for the synthesis of L-cysteine unsymmetrical disulfides under mild conditions with good to excellent yields. Described method is based on the straightforward preparation of the organophosphorus sulfenyl bromide readily available from bis-(5,5-dimethyl-2-thiono-1,3,2-dioxaphosphorinanyl) disulfide. The unsymmetrical disulfides can be obtained for L-cysteine derivatives and thiols bearing neutral...

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Year 2007

• Functionalization of cysteine derivatives by unsymmetrical disulfide bond formation

  Publication

  • J. Rachoń
  • D. Witt
  • S. Demkowicz
  • M. Szymelfejnik

  - SYNTHESIS-STUTTGART - Year 2007

  Opracowano metodę funkcjonalizacji pochodnych cysteiny przy pomocy tworzenia niesymetrycznego wiązania disulfidowego. Opracowana metoda okazała się bardzo łagodna, wydajna, i niewrażliwa na obecność dodatkowych grup funkcyjnych.

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