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The organophosphorus sulfenyl bromides as versatile reagents for cysteine derivatives functionalization by unsymmetrical disulfide bond formation
Abstract
We have developed a convenient method for the synthesis of L-cysteine unsymmetrical disulfides under mild conditions with good to excellent yields. Described method is based on the straightforward preparation of the organophosphorus sulfenyl bromide readily available from bis-(5,5-dimethyl-2-thiono-1,3,2-dioxaphosphorinanyl) disulfide. The unsymmetrical disulfides can be obtained for L-cysteine derivatives and thiols bearing neutral or acidic functionalities.
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- Category:
- Articles
- Type:
- artykuł w czasopiśmie z listy filadelfijskiej
- Published in:
-
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS
no. 2-3,
pages 415 - 419,
ISSN: 1042-6507 - Language:
- English
- Publication year:
- 2008
- Bibliographic description:
- Szymelfejnik M., Demkowicz S., Witt D., Rachoń J.: The organophosphorus sulfenyl bromides as versatile reagents for cysteine derivatives functionalization by unsymmetrical disulfide bond formation// PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS. -Vol. 2-3., (2008), s.415-419
- DOI:
- Digital Object Identifier (open in new tab) 10.1080/10426500701735437
- Verified by:
- Gdańsk University of Technology
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