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prof. dr hab. Michal Markuszewski
Employment
- 2016 - present professor, head of department at Medical University of Gdansk
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total: 128
Catalog Publications
Year 2022
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New approach in determination of urinary diagnostic markers for prostate cancer by MALDI-TOF/MS
Publication
Year 2021
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A Robust Method for Sample Preparation of Gastrointestinal Stromal Tumour for LC/MS Untargeted Metabolomics
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Comprehensive Metabolic Signature of Renal Dysplasia in Children. A Multiplatform Metabolomics Concept
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Development and optimization of modified nucleosides and deoxynucleosides simultaneous extraction with the use of Design of Experiments approach
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Effects of perineural administration of ropivacaine combined with perineural or intravenous administration of dexmedetomidine for sciatic and saphenous nerve blocks in dogs
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Lipidomics as a Diagnostic Tool for Prostate Cancer
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Metabolic Evaluation of Urine from Patients Diagnosed with High Grade (HG) Bladder Cancer by SPME-LC-MS Method
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Nanostructured Lipid Carriers Engineered as Topical Delivery of Etodolac: Optimization and Cytotoxicity Studies
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Perspectives and challenges in extracellular vesicles untargeted metabolomics analysis
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The Application of Metabolomics in Forensic Science with Focus on Forensic Toxicology and Time-of-Death Estimation
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The potential role of fatty acids in prostate cancer determined by GC–MS analysis of formalin-fixed paraffin-embedded tissue samples
Publication
Year 2020
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An Overview of the Application of Systems Biology in an Understanding of Chronic Rhinosinusitis (CRS) Development
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Comparison of Pteridine Normalization Methods in Urine for Detection of Bladder Cancer
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GC-MS-based untargeted metabolomics of plasma and urine to evaluate metabolic changes in prostate cancer
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Metabolomic Insight into Polycystic Ovary Syndrome—An Overview
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Metabolomic Signature of Early Vascular Aging (EVA) in Hypertension
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Proof-of-concept study on improved efficacy of rHuEPO administered as a long-term infusion in rats
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The Characterization of Ground Raspberry Seeds and the Physiological Response to Supplementation in Hypertensive and Normotensive Rats
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The Correlation between Physical Crosslinking and Water-Soluble Drug Release from Chitosan-Based Microparticles
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The Luminescence of 1,8-Diazafluoren-9-One/Titanium Dioxide Composite Thin Films for Optical Application
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Utilizing Genome-Wide mRNA Profiling to Identify the Cytotoxic Chemotherapeutic Mechanism of Triazoloacridone C-1305 as Direct Microtubule Stabilization
PublicationRational drug design and in vitro pharmacology profiling constitute the gold standard in drug development pipelines. Problems arise, however, because this process is often dicult due to limited information regarding the complete identification of a molecule’s biological activities. The increasing aordability of genome-wide next-generation technologies now provides an excellent opportunity to understand a compound’s diverse eects...
Year 2019
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Bayesian multilevel model of micro RNA levels in ovarian-cancer and healthy subjects
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Could spray-dried microbeads with chitosan glutamate be considered as promising vaginal microbicide carriers? The effect of process variables on the in vitro functional and physicochemical characteristics
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Design of Experiments in metabolomics-related studies: An overview
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Determination of Urinary Pterins by Capillary Electrophoresis Coupled with LED-Induced Fluorescence Detector
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Ethylcellulose in Organic Solution or Aqueous Dispersion Form in Designing Taste-Masked Microparticles by the Spray Drying Technique with a Model Bitter Drug: Rupatadine Fumarate
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Identification of the metabolic fingerprints in women with polycystic ovary syndrome using the multiplatform metabolomics technique
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Metabolomic Heterogeneity of Urogenital Tract Cancers Analyzed by Complementary Chromatographic Techniques Coupled with Mass Spectrometry
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Multiplatform metabolomics provides insight into the molecular basis of chronic kidney disease
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Paraffin-Embedded Tissue as a Novel Matrix in Metabolomics Study: Optimization of Metabolite Extraction Method
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Untargeted Metabolomics Provides Insight into the Mechanisms Underlying Resistant Hypertension
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Urinary metabolomic signature of muscle-invasive bladder cancer: A multiplatform approach
Publication
Year 2018
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Determination of tocopherols and tocotrienols in human breast adipose tissue with the use of high performance liquid chromatography-fluorescence detection
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Free silanols and ionic liquids as their suppressors in liquid chromatography
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Ionization of tocopherols and tocotrienols in atmospheric pressure chemical ionization
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New plasma preparation approach to enrich metabolome coverage in untargeted metabolomics: plasma protein bound hydrophobic metabolite release with proteinase K
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Ocular irritation and cyclosporine A distribution in the eye tissues after administration of Solid Lipid Microparticles in the rabbit model
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Targeted metabolomics in bladder cancer: From analytical methods development and validation towards application to clinical samples
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Urinary Nucleosides and Deoxynucleosides
Publication
Year 2017
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Combined computational-experimental approach to predict blood–brain barrier (BBB) permeation based on “green” salting-out thin layer chromatography supported by simple molecular descriptors
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Determination of amino acids in urine of patients with prostate cancer and benign prostate growth
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Evaluation of sample injection precision in respect to sensitivity in capillary electrophoresis using various injection modes
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How to model temporal changes in nontargeted metabolomics study? A Bayesian multilevel perspective
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HPLC–MS/MS method for dexmedetomidine quantification with Design of Experiments approach: application to pediatric pharmacokinetic study
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Migration time shift of analytes in micellar electrokinetic chromatography induced by stacking
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Multilevel pharmacokinetics-driven modeling of metabolomics data
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Overactive bladder treatment: application of methylene blue to improve the injection technique of onabotulinum toxin A
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Robust HPLC–MS/MS method for levofloxacin and ciprofloxacin determination in human prostate tissue
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Sample Concentration of Charged Small Molecules and Peptides in Capillary Electrophoresis by Micelle to Cyclodextrin Stacking
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Sample preparation procedures utilized in microbial metabolomics: An overview
Publication
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