Analysis of induction of DNA DSBs on telomeres in A549 cells - Open Research Data - Bridge of Knowledge

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Analysis of induction of DNA DSBs on telomeres in A549 cells

Description

Data consist of an analysis of DNA DSBs on telomeres. A549 were treated with compounds (TXT4, MTX, DMSO) at IC90 concentration for the indicated time. Images were acquired with an LSM 800 inverted laser scanning confocal microscope (Carl Zeiss; Dresden, Germany) equipped with an Airyscan detector using a ×63 1.4 NA Plan Apochromat objective (Carl Zeiss). Colocaliasation of spots (pH2AX and TRF2) was performed using ZEN system 2.3 (Carl Zeiss; Dresden, Germany) and exported to .txt format.

Dataset file

Analysis of induction of DNA DSBs on telomeres in A549 cells.zip
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download file Analysis of induction of DNA DSBs on telomeres in A549 cells.zip

File details

License:
Creative Commons: by-nc-sa 4.0 open in new tab
CC BY-NC-SA
Non-commercial - Share-alike
Raw data:
Data contained in dataset was not processed.

Details

Year of publication:
2022
Verification date:
2023-03-24
Dataset language:
English
Fields of science:
  • biological sciences (Natural sciences)
DOI:
DOI ID 10.34808/farj-4b08 open in new tab
Funding:
Series:
Verified by:
Gdańsk University of Technology

Keywords

References

  • publication Teloxantron inhibits the processivity of telomerase with preferential DNA damage on telomeres

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