Impact of binary mixtures of diclofenac and β-estradiol on endocrine processes of the model organism Saccharomyces Cerevisiae (using XenoScreen YES/YAS test) - with controls - Open Research Data - Bridge of Knowledge

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Impact of binary mixtures of diclofenac and β-estradiol on endocrine processes of the model organism Saccharomyces Cerevisiae (using XenoScreen YES/YAS test) - with controls

Description

Data shown in data set illustrate the results of the endocrine processes of mixtures of methylparaben and  β-estradiol  with controls for YES agonsit, YES antagonist, YAS agonist and YAS antagonist.  S cerevisiae is used as a model organism in the monitoring of endocrine disruptors in environmental and reference samples in Xenometrix® systems - XenoScreen®.  First substance namely diclofenac (sodium salt) is  non-steroidal anti-inflammatory drug and the second substance e.i β-estradiol is responsible for the development of the female reproductive organs, proliferation of the endometrium, regulates the sexual cycle and influences sexual behavior. The XenoScreen YES/YAS reagents and methodology is given in Kudłak et al. (2019) and in details in electronic supplementary material.

Studies were conducted between 2016 and 2017.
These results are part of the manuscript published in Science of the Total Environment

(Cyfrowy identyfikator dokumentu elektronicznego (otwiera się w nowej karcie)10.1016/j.scitotenv.2020.137358)

Illustration of the publication

Dataset file

Results YES YAS Diclofenac and β-estradiol.zip
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download file Results YES YAS Diclofenac and β-estradiol.zip

File details

License:
Creative Commons: by 4.0 open in new tab
CC BY
Attribution
Raw data:
Data contained in dataset was not processed.

Details

Year of publication:
2025
Verification date:
2025-02-28
Dataset language:
English
DOI:
DOI ID 10.34808/hmpz-hy07 open in new tab
Funding:
Series:
Verified by:
Gdańsk University of Technology

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