Search
Abstract
The purpose of this paper is to review recent developments on polyurethanes aimed at the design, synthesis, modifications, and biological properties in the field of bone tissue engineering. Different polyurethane systems are presented and discussed in terms of biodegradation, biocompatibility and bioactivity. A comprehensive discussion is provided of the influence of hard to soft segments ratio, catalysts, stiffness and hydrophilicity of polyurethanes. Interaction with various cells, behavior in vivo and current strategies in enhancing bioactivity of polyurethanes are described. The discussion on the incorporation of biomolecules and growth factors, surface modifications, and obtaining polyurethane-ceramics composites strategies is held. The main emphasis is placed on the progress of polyurethane applications in bone regeneration, including bone void fillers, shape memory scaffolds, and drug carrier.
Citations
-
1 1 7
CrossRef
-
0
Web of Science
-
1 2 0
Scopus
Authors (4)
Cite as
Full text
- Publication version
- Accepted or Published Version
- License
-
open in new tab
Keywords
Details
- Category:
- Articles
- Type:
- artykuł w czasopiśmie wyróżnionym w JCR
- Published in:
-
Materials Science & Engineering C-Materials for Biological Applications
no. 80,
pages 736 - 747,
ISSN: 0928-4931 - Language:
- English
- Publication year:
- 2017
- Bibliographic description:
- Mallach M., Kucińska-Lipka J., Kalaszczyńska I., Janik H.: Development of polyurethanes for bone repair// Materials Science & Engineering C-Materials for Biological Applications. -Vol. 80, (2017), s.736-747
- DOI:
- Digital Object Identifier (open in new tab) 10.1016/j.msec.2017.07.047
- Verified by:
- Gdańsk University of Technology
seen 236 times
Recommended for you
Degradable poly(ester-ether) urethanes of improved surface calcium deposition developed as novel biomaterials
- J. Kucińska-Lipka,
- A. Lewandowska,
- P. Szarlej
- + 2 authors