Drug-resistant and hospital-associated Enterococcus faecium from wastewater, riverine estuary and anthropogenically impacted marine catchment basin.

Ewa Sadowy; Aneta Łuczkiewicz

doi:10.1186/1471-2180-14-66

Drug-resistant and hospital-associated Enterococcus faecium from wastewater, riverine estuary and anthropogenically impacted marine catchment basin.

Abstract

Enterococci, ubiquitous colonizers of humans and other animals, play an increasingly important role in health-care associated infections (HAIs). Acquisition of resistance determinants not only seriously limits available therapeutic options but also increases available gene pool for other species. It is believed that the recent evolution of two clinically relevant species, Enterococcus faecalis and Enterococcus faecium occurred in a big part in a hospital environment, leading to formation of high-risk enterococcal clonal complexes (HiRECCs), which combine multidrug resistance with increased pathogenicity and epidemicity. The acquisition of drug resistance is, however, not limited to HiRECCs. Drug-resistant strains, of both HiRECC and non-HiRECC, are released to the environment by wastewaters at an unknown scale. The aim of this study was to establish the species composition in wastewaters at various sampling points, in a river estuary and their marine recipient, to investigate susceptibility of collected isolates to antimicrobials and to characterize drug-susceptible and -resistant enterococcal isolates by molecular methods, with the special focus on the most prevalent species, E. faecium and its HiRECC representatives.

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Authors (2)

Ewa Sadowy
Aneta Łuczkiewicz dr hab. inż.

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Keywords

ENTEROCOCCUS

Details

Category:: Articles
Type:: artykuł w czasopiśmie wyróżnionym w JCR
Published in:: BMC MICROBIOLOGY no. 14, edition 1, pages 1 - 15,
ISSN: 1471-2180
Language:: English
Publication year:: 2014
Bibliographic description:: Sadowy E., Łuczkiewicz A.: Drug-resistant and hospital-associated Enterococcus faecium from wastewater, riverine estuary and anthropogenically impacted marine catchment basin.// BMC MICROBIOLOGY. -Vol. 14, iss. 1 (2014), s.1-15
DOI:: Digital Object Identifier (open in new tab) 10.1186/1471-2180-14-66
Verified by:: Gdańsk University of Technology