Morphometric evaluation of the delayed cerebral arteries response to acetazolamide test in patients with chronic carotid artery stenosis using computed tomography angiography - Publication - Bridge of Knowledge

Your account

login

Search

Morphometric evaluation of the delayed cerebral arteries response to acetazolamide test in patients with chronic carotid artery stenosis using computed tomography angiography

Abstract

Background: The evidence accumulates that the response to acetazolamide test is delayed on the ipsilateral side to stenosis. However, the effect of acetazolamide beyond 30 minutes after acetazolamide administration remains unknown. The aim of this study was to assess the diameters of: anterior cerebral arteries (ACAs), middle cerebral arteries (MCAs) and posterior cerebral arteries (PCAs) before and 60 minutes after the acetazolamide test. Materials and Methods: Seventeen patients with carotid artery stenosis ≥90% on the ipsilateral side and, ≤50% on the contralateral side were enrolled into the study. Diagnosis was based on ultrasonography examination and was confirmed using digital subtractive angiography. In all patients, two computed tomography angiography examinations were carried out; the first was performed before the acetazolamide administration while the second one was carried out 60 minutes after injections. Results: In response to the acetazolamide test: PCA diameter diminished in both ipsi- and contra- lateral side to stenosis (from 1.31 to 1.24 mm and from 1.23 to 1.15, respectively), ACA and MCA decreased in the contralateral side to the stenosis (from 1.33 to 1.26 and from 2.75 to 2.66 mm, respectively), ACA and MCA increased in the ipsilateral side to the stenosis (from 1.29 to 1.46 mm and from 2.77 to 2.96, respectively). All changes were statistically significant. Conclusions: There were significant differences in reactivity to acetazolamide challenge between the internal carotid artery (ICA) and vertebra-basilar circulation in patients suffering from chronic carotid artery stenosis. Within the ICA territory ACAs and MCAs responses vary in the affected and not affected side.

Citations

  • 2

    CrossRef

  • 0

    Web of Science

  • 4

    Scopus

Authors (8)

Cite as

Full text

download paper
downloaded 25 times
Publication version
Accepted or Published Version
DOI:
Digital Object Identifier (open in new tab) 10.5603/FM.a2016.0034
License
Creative Commons: CC-BY-NC-ND open in new tab

Keywords

Details

Category:
Articles
Type:
artykuł w czasopiśmie wyróżnionym w JCR
Published in:
Folia Morphologica no. 76, edition 1, pages 10 - 14,
ISSN: 0015-5659
Language:
English
Publication year:
2017
Bibliographic description:
Szarmach A., Winklewski P. J., Halena G., Kaszubowski M. F., Dzierżanowski J., Piskunowicz M., Szurowska E., Frydrychowski A.: Morphometric evaluation of the delayed cerebral arteries response to acetazolamide test in patients with chronic carotid artery stenosis using computed tomography angiography// Folia Morphologica. -Vol. 76, iss. 1 (2017), s.10-14
DOI:
Digital Object Identifier (open in new tab) 10.5603/fm.a2016.0034
Verified by:
Gdańsk University of Technology

seen 130 times

Recommended for you

Regional resting state perfusion variability and delayed cerebrovascular uniform reactivity in subjects with chronic carotid artery stenosis

2018

Computed tomography indicators of cerebral microperfusion improve long term after carotid stenting in symptomatic patients

2020

Perfusion computed tomography: 4 cmversus8 cm coverage size in subjects with chronic carotid artery stenosis

2016

Carotid Artery Stenting and Blood–Brain Barrier Permeability in Subjects with Chronic Carotid Artery Stenosis

2017
Meta Tags