Polymers for burn dressings and skin substitutes

Przemysław Gnatowski; Karolina Gwizdała; Edyta Piłat; Justyna Kucińska-Lipka

doi:10.1016/b978-0-323-99690-7.00011-x

Polymers for burn dressings and skin substitutes

Abstract

Skin burns belong to the group of the most complex injuries due to convoluted skin structure which includes nerve cells, muscles, sweat and sebaceous glands and blood vessels. Both on the market and at the research stage, there are many different dressing and skin substitutes proposals that utilize various materials and active substances. This chapter focuses on summarizing and describing the most popular polymer-based commercial products currently in use and the main lines of research for skin burn treatments. The most common materials used in commercial products are collagen, fibroblasts, polyurethanes and various hydrogels. In current research there is more emphasis placed on modifying materials with synthetic active substances, nanoparticles and incorporation of well-known natural materials such as curcumin, chitosan or propolis. Despite the great achievements in the field of burn treatment, the developed solutions are not perfect. In the case of advanced commercial products containing human cells, a great barrier to widespread application is their high price, and simpler solutions are still insufficiently effective. In short time there is a perspective of the introduction to the market of products with high efficiency and moderate price, modified with nanoparticles and substances of natural origin. Some of those materials are currently undergoing clinical trials and FDA approval process.

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Keywords

POLYMERS,BURN DRESSINGS, SKIN SUBSTITUTES

Details

Category:

Monographic publication

Type:

rozdział, artykuł w książce - dziele zbiorowym /podręczniku w języku o zasięgu międzynarodowym

Language:

English

Publication year:

2023

Bibliographic description:

Gnatowski P., Gwizdała K., Piłat E., Kucińska-Lipka J.: Chapter 13 - Polymers for burn dressings and skin substitutes// Polymers for burn dressings and skin substitutes/ : , , s.319-336

DOI: