Search results for: OCTAARGININE - Bridge of Knowledge

Search results for: OCTAARGININE

Found little results, maybe try searching with alternative method.

Filters

total: 1

clear all filters disabled

Best results in : Research Potential Pokaż wszystkie wyniki (1)

Katedra Technologii Leków i Biochemii
Research Potential
- Department of Pharmaceutical Technology and Biochemistry
Racjonalne projektowanie, synteza i badanie właściwości biologicznych nowych związków o działaniu przeciwnowotworowym lub przeciwgrzybowym

Other results Pokaż wszystkie wyniki (2)

The Effect of Conjugation with Octaarginine, a Cell-Penetrating Peptide on Antifungal Activity of Imidazoacridinone Derivative
Publication
- K. Rząd
- E. Paluszkiewicz
- D. Neubauer
- M. Olszewski
- K. Kozłowska-Tylingo
- W. Kamysz
- I. Gabriel
- INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - Year 2021
Acridine cell-penetrating peptide conjugates are an extremely important family of compounds in antitumor chemotherapy. These conjugates are not so widely analysed in antimicrobial therapy, although bioactive peptides could be used as nanocarriers to smuggle antimicrobial compounds. An octaarginine conjugate of an imidazoacridinone derivative (Compound 1-R8) synthetized by us exhibited high antifungal activity against reference...

Full text available to download
Killing kinetics analysis of C-1311 derivative with octaarginine (Compound 1-R8) against Candida albicans
Open Research Data
open access
- K. Rząd
- D. Neubauer
- I. Gabriel
- E. Paluszkiewicz
- K. Kozłowska-Tylingo
- W. Kamysz
- series: C-1305, C-1311
The datasets contain the results of killing kinetics analysis of imidazoacridinone derivative and fluconazole against C. albicans ATCC 10231. The suspensions of Candida albicans ATCC 10231 cells (500 µL) in RPMI 1640 at cell density of 104 cells /mL were added to 500 µL of RPMI 1640 medium with various concentrations of the compounds, corresponding...