Search results for: UDP-GLUCURONYLTRANSFERASES

Search results for: UDP-GLUCURONYLTRANSFERASES

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Katedra Technologii Leków i Biochemii
Research Potential
- Department of Pharmaceutical Technology and Biochemistry
Racjonalne projektowanie, synteza i badanie właściwości biologicznych nowych związków o działaniu przeciwnowotworowym lub przeciwgrzybowym

The II phase metabolism of endogenous and exogenous compounds, including antitumor chemotherapeutics
Publication
- Year 2014
The II phase metabolism, it is a set of metabolism and excretion pathways of endogenous as well as exogenous compounds including xenobiotics. UDP-glucuronyltransferases (UGTs; EC 2.4.1.17) are the most crucial representatives of II phase enzymes, which are responsible for the transformation of bilirubine and bile acids, steroids and thyroid hormones and lipids. Exogenous compounds, including drugs, carcinogens, environmental pollutants...