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Search results for: intestinalin

  • A Novel Cryptic Clostridial Peptide That Kills Bacteria by a Cell Membrane Permeabilization Mechanism

    Publication
    • M. Szadkowska
    • M. Olewniczak
    • A. Kloska
    • E. Jankowska
    • M. Kapusta
    • B. Rybak
    • D. Wyrzykowski
    • W. Zmudzinska
    • A. Gieldon
    • A. Kocot... and 5 others

    - Microbiology Spectrum - Year 2022

    This work reports detailed characteristics of the antimicrobial peptide Intestinalin (P30), which is derived from the LysC enzyme of Clostridium intestinale strain URNW. The peptide shows a broader antibacterial spectrum than the parental enzyme, showing potent antimicrobial activity against clinical strains of Gram-positive staphylococci and Gram-negative pathogens and causing between 3.04 ± 0.12 log kill for Pseudomonas aeruginosa...

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