Year 2022

• New 2-[(4-Amino-6-N-substituted-1,3,5-triazin-2-yl)methylthio]-N-(imidazolidin-2-ylidene)-4-chloro-5-methylbenzenesulfonamide Derivatives, Design, Synthesis and Anticancer Evaluation

  Publication

  • Ł. Tomorowicz
  • B. Żołnowska
  • K. Szafrański
  • J. Chojnacki
  • R. Konopiński
  • E. A. Grzybowska
  • J. Sławiński
  • A. Kawiak

  - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - Year 2022

  In the search for new compounds with antitumor activity, new potential anticancer agents were designed as molecular hybrids containing the structures of a triazine ring and a sulfonamide fragment. Applying the synthesis in solution, a base of new sulfonamide derivatives 20–162 was obtained by the reaction of the corresponding esters 11–19 with appropriate biguanide hydrochlorides. The structures of the compounds were confirmed...

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Year 2010

• [N,N'-Bis(2,6-diisopropylphenyl)pentane-2,4-diamine(1-)-2[kappa]2N,N']-[mu]2-chlorido-1:2[kappa]2Cl:Cl-chlorido-2[kappa]Cl-bis(1,2-dimethoxyethane-1[kappa]2O,O')iron(II)lithium

  Publication

  • R. Grubba
  • Ł. Ponikiewski
  • Ł. Tomorowicz
  • J. Pikies

  - ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE - Year 2010

  In the title compound, [FeLi(C29H41N2)Cl2(C4H10O2)2], theFeII atom is coordinated by two N and two Cl atoms,generating a distorted FeN2Cl2 tetrahedral geometry. Additionally,one of the chloride atoms bridges to a lithium ion,which is solvated by two dimethoxyethane molecules and iscoordinated in a distorted trigonal-bipyramidal environment.The central Fe, Cl (*2) and Li atoms are coplanar with amaximum deviation of 0.034 A ° .

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