Minimum inhibitory concentrations (MICs) determination of selected human topoisomerase II alpha and bacterial DNA gyrase inhibitors against fungal strains - Open Research Data - Bridge of Knowledge

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Minimum inhibitory concentrations (MICs) determination of selected human topoisomerase II alpha and bacterial DNA gyrase inhibitors against fungal strains

Description

The datasets contain the results of determining the MIC (Minimal Inhibitory Concentration) value of known compounds* (inhibitors of human topoisomerase II alpha and bacterial DNA gyrase) against C. albicans SC5314, C. glabrata ATCC 90030, C. krusei ATCC 6258 and C. parapsilosis ATCC 22019 and Saccharomyces cerevisiae ATCC 9763 by the modified M27-A3 specified by the CLSI.

*Compounds:

  • ciprofloxacin
  • levofloxacin
  • etoposide
  • quinacrine
  • bisantrene
  • pixantrone
  • resveratrol
  • teniposide
  • dexrazoxane
  • mitoxantrone
  • daunorubicin
  • doxorubicin
  • epirubicin
  • idarubicin
  • valrubicin
  • merbarone
  • novobiocin

Dataset file

MIC inhibitors hTOPOII, DNA gyrase.zip
511.0 kB, S3 ETag 92decf5e61879cd19594f838e5f97270-1, downloads: 50
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hexmd5(md5(part1)+md5(part2)+...)-{parts_count} where a single part of the file is 512 MB in size.

Example script for calculation:
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download file MIC inhibitors hTOPOII, DNA gyrase.zip

File details

License:
Creative Commons: by 4.0 open in new tab
CC BY
Attribution
Raw data:
Data contained in dataset was not processed.
Software:
Excel

Details

Year of publication:
2024
Verification date:
2024-07-03
Dataset language:
English
Fields of science:
  • chemical sciences (Natural sciences)
DOI:
DOI ID 10.34808/0kz4-y909 open in new tab
Funding:
Verified by:
Gdańsk University of Technology

Keywords

References

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