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Development of novel bifunctional ceramic coatings with osteoinductive and anti-oncogenic properties on metallic implants dedicated to the bone reconstruction after tumor resection obtained via the dual-step ultrasonic micro-arc oxidation
The aim of the project is to develop, produce and characterize bifunctional ceramic coatings on titanium alloy and magnesium for the treatment of bone tissue, especially in the case of bone cancer. The proposed calcium-phosphate coatings will have osteoinductive properties, and the addition of a drug or selenium compounds should provide the material anti-oncogenic properties. The proposed solution should improve the biological response and mechanical properties of biomaterials, as well as ensure their anti-oncogenic properties. The main technical problem to be solved within the project will be the development of the appropriate chemical composition of the electrolyte and the selection of parameters for the ultrasonic-assisted micro-arc oxidation process.
Details
- Financial Program Name:
- PRELUDIUM
- Organization:
- Narodowe Centrum Nauki (NCN) (National Science Centre)
- Realisation period:
- 2024-01-09 - 2027-01-08
- Project manager:
- mgr inż. Balbina Makurat-Kasprolewicz
- Team members:
-
- Mentor dr inż. Mohammad Saeb
- Realised in:
- Zakład Konstrukcji Maszyn i Inzynierii Medycznej
- Project's value:
- 209 880.00 PLN
- Request type:
- National Research Programmes
- Domestic:
- Domestic project
- Verified by:
- Gdańsk University of Technology
Papers associated with that project
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Catalog Projects
Year 2024
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Effect of ultrasound on the physicochemical, mechanical and adhesive properties of micro-arc oxidized coatings on Ti13Nb13Zr bio-alloy
PublicationImplant surgeries are increasingly challenging due to their rising number. Achieving the desired biomaterial surface properties to ensure a strong bond with human tissue is a significant issue. This study investigates the influence of ultrasound (US) during the micro-arc oxidation (MAO) process on Ti13Zr13Nb bio-alloy, an area not previously explored, to enhance titanium alloy coatings’ properties for biomedical applications. Porous...
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