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- Category:
- Other publications
- Type:
- Other publications
- Title of issue:
- Clozapine Induced Myocarditis: a case report strony 58 - 61
- Publication year:
- 2024
- Bibliographic description:
- Clozapine is commonly used in resistant schizophrenia, but its use has been limited because of side effects. Myocarditis is one of the rare and potentially fatal side effects that can occur at any time after initiation of treatment but typically occurs within 2 to 3 weeks after initiation treatment with clozapine. We report the case of a 28-year-old patient who developed myocarditis after initiation treatment with clozapine, and a successful re-challenge of starting Clozapine. The physician should be cautious during the initiation of rapid clozapine titration early in treatment and follow the guidelines of close monitoring with laboratory investigation. This allows the early detection of myocarditis and reduces the risk of fatal mortality.
- Bibliography: test
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- De Berardis D, Serroni N, Campanella D, Olivieri L, Ferri F, et al. Update on the adverse effects of clozapine: focus on myocarditis. Curr Drug Saf 2012;7:55-62. open in new tab
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- Ronaldson KJ, Fitzgerald PB, Taylor AJ, Topliss DJ, Wolfe R, McNeil JJ. Rapid clozapine dose titration and concomitant sodium valproate increase the risk of myocarditis with clozapine: A case-control study. Schizophr Res 2012;141:173-8. open in new tab
- Haas SJ, Hill R, Krum H, Liew D, Tonkin A, Demos L, Stephan K, et al. Clozapine-associated myocarditis: a review of 116 cases of suspected myocarditis associated with the use of clozapine in Australia during 1993- 2003. Drug Saf 2007;30:47-57. open in new tab
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