Search results for: RNA

• RNA-A PUBLICATION OF THE RNA SOCIETY

  Journals

  ISSN: 1355-8382 , eISSN: 1469-9001

• Mechanism of reaction of RNA-dependent RNA polymerase from SARS-CoV-2

  Publication

  • J. Aranda
  • M. Wieczór
  • M. Terrazas
  • I. Brun-Heath
  • M. Orozco

  - Chem Catalysis - Year 2022

  We combine molecular dynamics, statistical mechanics, and hybrid quantum mechanics/molecular mechanics simulations to describe mechanistically the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA-dependent RNA polymerase (RdRp). Our study analyzes the binding mode of both natural triphosphate substrates as well as remdesivir triphosphate (the active form of drug), which is bound preferentially over ATP by RdRp while...

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• NASBA – IZOTERMICZNA AMPLIFIKACJA RNA

  Publication

  • M. Kordalewska

  - Dokonania Młodych Naukowców - Year 2014

  NASBA (ang. Nucleic Acid Sequence-Based Amplification) jest skuteczną i czułą techniką izotermicznej amplifikacji opartej na transkrypcji, służąca głównie do detekcji cząsteczek RNA. Znalazła ona zastosowanie do wykrywania RNA wirusowego, bakteryjnego i grzybiczego w próbkach klinicznych oraz żywości.

• Non-coding RNA

  Journals

  eISSN: 2311-553X

• Journal of RNA and Genomics

  Journals

  ISSN: 2591-7781

• Early Stages of RNA-Mediated Conversion of Human Prions

  Publication

  • E. Lubecka
  • U. H. E. Hansmann

  - JOURNAL OF PHYSICAL CHEMISTRY B - Year 2022

  Prion diseases are characterized by the conversion of prion proteins from a PrPC fold into a disease-causing PrPSC form that is self-replicating. A possible agent to trigger this conversion is polyadenosine RNA, but both mechanism and pathways of the conversion are poorly understood. Using coarse-grained molecular dynamic simulations we study the time evolution of PrPC over 600 μs. We find that both the D178N mutation and interacting...

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•  The structure and role of mammalian sperm RNA: a review

  Publication

  • D. Bukowska
  • B. Kempisty
  • H. Piotrowska
  • P. Sosinska
  • M. Wozna
  • S. Ciesiolka
  • P. Antosik

  - VETERINARNI MEDICINA - Year 2013

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• SERRATE: a key factor in coordinated RNA processing in plants

  Publication

  • M. Jozwiak
  • D. Bielewicz
  • Z. Szweykowska-Kulinska
  • A. Jarmolowski
  • M. Bajczyk

  - Trends in Plant Science - Year 2023

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• SiMiSnoRNA: Collection of siRNA, miRNA, and snoRNA database for RNA Interference

  Publication

  • U. Kalathiya
  • M. Padariya
  • M. Bagiński
  • C. Padariya

  - Turkish Journal of Biochemistry-Turk Biyokimya Dergisi - Year 2015

  Objective:The discovery of sequence specific gene silencing which occurs due to the presence of double-stranded RNAs has considerable impact on biology, revealing an unknown level of regulation of gene expression. This process is known as RNA interference (RNAi) or RNA silencing in which RNA molecules inhibit gene expression, typically by causing the destruction of specific mRNA molecule. Two types of small RNA molecules - small...

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• EASY ACCESS TOOL FOR SMALL INTERFERING RNA (siRNA) DATA

  Publication

  • M. Padariya
  • U. Kalathiya

  - Year 2015

  For many decades it was an accepted dogma of molecular genetics that the expression of genes is a “one-way-road” leading only in one direction from DNA to RNA to proteins. Recent discoveries in modern molecular genetics have challenged this dogma showing that specific RNA molecules play a central role in controlling the activity of genes by changing the structure of DNA sequences, targeting other RNAs for degradation or blocking...

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