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Dietary intervention with beetroot juice during doxorubicin cancer chemotherapy in vivo reduces markers of oxidative stress
Publication
- J. Łukowicz
- G. Peszyńska-Sularz
- A. Cieślak
- A. Piasek
- M. Janicka
- A. Kot-Wasik
- S. Popadiuk
- W. Grajek
- A. Bartoszek-Pączkowska
- Acta Biochimica Polonica - Year 2012
Cancer chemotherapy with doxorubicin, despite high antitumor activity and broad spectrum of this drug, is on decline due to toxic side effects. The clinical efficacy of anthracyclines have continuously prompted the search for new adjuvants to alleviate undesirable side toxicity incurred by this group of cytostatics. The recent approaches involve the application of synthetic or purified natural antioxidants in combination with doxorubicin...