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Search results for: molecular biology and genetics
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SABRAO Journal of Breeding and Genetics
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JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
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JOURNAL OF ANIMAL BREEDING AND GENETICS
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Twin Research and Human Genetics
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Spectroscopic studies on physicochemical properties of selected unsymmetrical bisacridine derivatives and NMR analysis of their interactions with the model sequence Pu22 aided by molecular dynamics
PublicationIn recent years, new promising acridine derivatives have appeared, belonging to the unsymmetrical bisacridines (UAs) family with high anticancer activity. Both their physicochemical properties and their mechanism of action at the molecular level have not been thoroughly analyzed so far. Four derivatives were selected for the study, termed as: C-2028, C-2041, C-2045 and C-2053. The first aim of this work was to determine the protonation...
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Molecular biaxiality determines the helical structure – infrared measurements of the molecular order in the nematic twist-bend phase of difluoro terphenyl dimer
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Conformational studies of [Nphe5]SFTI-1 by means of 2D NMR spectroscopy in conjunction with molecular dynamics calculations
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Intramolecular transformation of an antifungal antibiotic nystatin A1 into its isomer, iso-nystatin A1 - structural and molecular modeling studies
PublicationNystatin A1, a polyene macrolide antifungal antibiotic, in a slightly basic or acidic solution undergoes an intramolecular transformation, yielding a structural isomer, the translactonization product, iso-nystatin A1 with lactone ring diminished by two carbon atoms. Structural evidence is provided by advanced NMR and Mass Spectrometry (MS) studies. Molecular dynamics simulations and quantum mechanics calculations gave the insight...
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HUMAN GENETICS
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Are the short cationic lipopeptides bacterial membrane disruptors? Structure-Activity Relationship and molecular dynamic evaluation
PublicationShort cationic lipopeptides are amphiphilic molecules that exhibit antimicrobial activity mainly against Grampositives. These compounds bind to bacterial membranes and disrupt their integrity. Here we examine the structure-activity relation (SAR) of lysine-based lipopeptides, with a prospect to rationally design more active compounds. The presented study aims to explain how antimicrobial activity of lipopeptides is affected by...
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CURRENT BIOLOGY
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CONSERVATION BIOLOGY
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ZOO BIOLOGY
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BIOLOGY BULLETIN
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Biology Direct
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BIOLOGY OF REPRODUCTION
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WILDLIFE BIOLOGY
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BIOLOGY & PHILOSOPHY
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BIOLOGY OF THE CELL
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Biology of Sport
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CHEMISTRY & BIOLOGY
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DEVELOPMENTAL BIOLOGY
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ADDICTION BIOLOGY
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BMC BIOLOGY
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Biology Letters
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Evolutionary Biology
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Biology Open
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Open Biology
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Redox Biology
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Fungal Biology
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FRESHWATER BIOLOGY
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GENOME BIOLOGY
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BIOLOGY OF THE NEONATE
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PLOS BIOLOGY
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HUMAN BIOLOGY
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Quantitative Biology
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In Silico Biology
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HISTORICAL BIOLOGY
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Annals of Biology
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Integrative Biology
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Cogent Biology
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Frontiers in Biology
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Subterranean Biology
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Synthetic Biology
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MARINE BIOLOGY
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MATRIX BIOLOGY
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INVERTEBRATE BIOLOGY
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Primate Biology
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