Search results for: ASTROCYTES

• Nitric Oxide-Dependent Pathways as Critical Factors in the Consequences and Recovery after Brain Ischemic Hypoxia

  Publication

  • J. M. Wierońska
  • P. Cieślik
  • L. Kalinowski

  - Biomolecules - Year 2021

  Brain ischemia is one of the leading causes of disability and mortality worldwide. Nitric oxide (NO), a molecule that is involved in the regulation of proper blood flow, vasodilation, neuronal and glial activity constitutes the crucial factor that contributes to the development of pathological changes after stroke. One of the early consequences of a sudden interruption in the cerebral blood flow is the massive production of reactive...

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• Natural fish oil improves the differentiation and maturation of oligodendrocyte precursor cells to oligodendrocytes in vitro after interaction with the blood–brain barrier

  Publication

  • P. Piatek
  • N. Lewkowicz
  • S. Michlewska
  • M. Wieczorek
  • R. Bonikowski
  • K. Parchem
  • P. Lewkowicz
  • M. Namiecinska

  - Frontiers in Immunology - Year 2022

  The blood–brain barrier (BBB) tightly controls the microenvironment of the central nervous system (CNS) to allow neurons to function properly. Additionally, emerging studies point to the beneficial effect of natural oils affecting a wide variety of physiological and pathological processes in the human body. In this study, using an in vitro model of the BBB, we tested the influence of natural fish oil mixture (FOM) vs. borage oil...

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