Search results for: PROTEIN DIMERISATION

• Inhibition of amyloid fibril formation of hen egg white lysozyme by trimethylamine N-oxide at low pH

  Publication

  • J. Wawer
  • J. Krakowiak
  • M. Szociński
  • Z. Lustig
  • M. Olszewski
  • K. Szostak

  - INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES - Year 2014

  In vitro inhibition of the formation of fibrous aggregates of proteins (amyloids) has gained increasing attention due to the number of diseases associated with protein misfolding and fibrillation. An interesting group of compounds for which pronounced activity against this phenomenon can be expected consists of low molecular weight substances (osmolytes) which have the ability to change protein stability. Here we investigate the...

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