Search results for: S(+)-CLENBUTEROL

• Abuse or contamination? Ratio determination of clenbuterol enantiomers to distinguish between doping use and meat contamination

  Publication

  • M. Thijs
  • M. K. Parr
  • M. Blokland
  • F. Liebetrau
  • A. Schmidt
  • M. Stanic
  • E. Waraksa
  • D. Kwiatkowska
  • S. Sterk

  - Year 2016

  Clenbuterol has been detected in urine of several athletes during routine doping control in the past years. Athletes claimed that the clenbuterol was ingested by eating contaminated meat. Providing analytical prove for this claim is difficult. clenbuterol consists of two enantiomers, R(-) and S(+)-clenbuterol. Currently available human and veterinary preparations were found to consist of a racemic mixture of both enantiomers. When...

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• Distinction of clenbuterol intake from drug or contaminated food of animal origin in a controlled administration trial – the potential of enantiomeric separation for doping control analysis

  Publication

  • M. K. Parr
  • M. Blokland
  • F. Liebetrau
  • A. Schmidt
  • T. Meijer
  • M. Stanic
  • D. Kwiatkowska
  • E. Waraksa
  • S. Sterk

  - Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure& Risk Assessment - Year 2017

  The differentiation of clenbuterol abuse and unintentional ingestion by contaminated meat is crucial with respect to the valuation of an adverse analytical finding in human sports doping control. The proportion of the two enantiomers of clenbuterol may serve as potential discriminating parameter. For the determination of the individual enantiomers, specific methods were developed and validated for the different matrices under investigation...

  Full text to download in external service