Search results for: SPLICE VARIANTS - Bridge of Knowledge

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Search results for: SPLICE VARIANTS

Search results for: SPLICE VARIANTS

  • Survivin splice variants expression in thyroid malignancy

    Publication
    • J. Waligorska-Stachura
    • N. Sawicka-Gutaj
    • M. Andrusiewicz
    • M. Biczysko
    • A. Jankowska
    • M. Ruchala
    • M. Andrusiewicz

    - Endocrine Abstracts - Year 2014

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  • Evaluation of survivin splice variants in pituitary tumors

    Publication
    • J. Waligórska-Stachura
    • M. Andrusiewicz
    • N. Sawicka-Gutaj
    • M. Kubiczak
    • A. Jankowska
    • W. Liebert
    • A. Czarnywojtek
    • R. Waśko
    • A. Blanco-Gangoo
    • M. Ruchała

    - PITUITARY - Year 2015

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  • Splice variants of mitofusin 2 shape the endoplasmic reticulum and tether it to mitochondria

    Publication
    • D. Naón
    • M. I. Hernández-Alvarez
    • S. Shinjo
    • M. Wieczór
    • S. Ivanova
    • O. Martins de Brito
    • A. Quintana
    • J. Hidalgo
    • M. Palacín
    • P. Aparicio... and 9 others

    - SCIENCE - Year 2023

    In eukaryotic cells, different organelles interact at membrane contact sites stabilized by tethers. Mitochondrial mitofusin 2 (MFN2) acts as a membrane tether that interacts with an unknown partner on the endoplasmic reticulum (ER). In this work, we identified the MFN2 splice variant ERMIT2 as the ER tethering partner of MFN2. Splicing of MFN2 produced ERMIT2 and ERMIN2, two ER-specific variants. ERMIN2 regulated ER morphology,...

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  • Transcriptomic landscape of blood platelets in healthy donors

    Publication
    • A. Supernat
    • M. Popęda
    • K. Pastuszak
    • M. G. Best
    • P. Grešner
    • S. I. ’. Veld
    • B. Siek
    • N. Bednarz-Knoll
    • M. T. Rondina
    • T. Stokowy... and 3 others

    - Scientific Reports - Year 2021

    Blood platelet RNA-sequencing is increasingly used among the scientific community. Aberrant platelet transcriptome is common in cancer or cardiovascular disease, but reference data on platelet RNA content in healthy individuals are scarce and merit complex investigation. We sought to explore the dynamics of platelet transcriptome. Datasets from 204 healthy donors were used for the analysis of splice variants, particularly with...

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  • Transcriptomic landscape of blood platelets in healthy donors

    Publication
    • A. Supernat
    • M. Popęda
    • K. Pastuszak
    • M. G. Best
    • P. Gresner
    • S. In ‘t Veld
    • B. Siek
    • N. Bednarz-Knoll
    • M. T. Rondina
    • T. Stokowy... and 3 others

    - Scientific Reports - Year 2021

    BACKGROUND Blood platelet RNA-sequencing is increasingly used among the scientific community. Aberrant platelet transcriptome is common in cancer or cardiovascular disease, but reference data on platelet RNA content in healthy individuals are scarce and merit complex investigation. METHODS We sought to explore the dynamics of platelet transcriptome. Datasets from 204 healthy donors were used for the analysis of splice variants,...

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  • Platelet RNA Sequencing Data Through the Lens of Machine Learning

    Publication

    - Cancers - Year 2023

    Liquid biopsies offer minimally invasive diagnosis and monitoring of cancer disease. This biosource is often analyzed using sequencing, which generates highly complex data that can be used using machine learning tools. Nevertheless, validating the clinical applications of such methods is challenging. It requires: (a) using data from many patients; (b) verifying potential bias concerning sample collection; and (c) adding interpretability...

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