Search results for: pharmacokinetics

• Optimal inputs in pharmacokinetics model's identification

  Publication

  • A. Pietrenko-Dąbrowska
  • R. Kalicka

  - Biocybernetics and Biomedical Engineering - Year 2006

  W pracy przedstawiono zagadnienie optymalizacji pobudzeń dla identyfikacji parametrycznej kompartmentowych modeli zmiennych stanu SISO systemów farmakokinetycznych. Zaimplementowano kryterium w postaci śladu macierzy informacyjnej Fishera (kryterium czułościowe). Rozważono klasę pobudzeń dopuszczalnych o ograniczonej energii, gdyż w przypadku wielu leków zbyt szybkie ich podawanie wiąże się z występowaniem skutków ubocznych. Zadanie...

• Nonstationary Pharmacokinetics of Caspofungin in ICU Patients

  Publication

  • A. Borsuk-De
  • J. Sysiak-Sławecka
  • E. Rypulak
  • M. Borys
  • P. Piwowarczyk
  • G. Raszewski
  • D. Onichimowski
  • M. Czuczwar
  • P. Wiczling

  - ANTIMICROBIAL AGENTS AND CHEMOTHERAPY - Year 2020

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• Drug Metabolism and Pharmacokinetics

  Journals

  ISSN: 1347-4367 , eISSN: 1880-0920

• JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

  Journals

  ISSN: 1567-567X , eISSN: 1573-8744

• Multilevel pharmacokinetics-driven modeling of metabolomics data

  Publication

  • E. Daghir-Wojtkowiak
  • P. Wiczling
  • M. Waszczuk-Jankowska
  • R. Kaliszan
  • M. Markuszewski
  • M. Markuszewski

  - METABOLOMICS - Year 2017

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• The influence of the time of day on midazolam pharmacokinetics and pharmacodynamics in rabbits

  Publication

  • A. Bienert
  • W. Płotek
  • P. Wiczling
  • B. Kostrzewski
  • A. Kamińska
  • H. Billert
  • D. Szczesny
  • C. Żaba
  • A. Teżyk
  • K. Buda... and 3 others

  - Pharmacological Reports - Year 2014

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• Influence of Time of Day on Propofol Pharmacokinetics and Pharmacodynamics in Rabbits

  Publication

  • A. Bienert
  • W. Płotek
  • I. Zawidzka
  • N. Ratajczak
  • D. Szczesny
  • P. Wiczling
  • Z. Kokot
  • J. Matysiak
  • E. Grześkowiak

  - Chronobiology International - Year 2011

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• Central Metal Determines Pharmacokinetics of Chlorophyll-Derived Xenobiotics

  Publication

  • M. Szczygieł
  • K. Urbańska
  • P. Jurecka
  • I. Stawoska
  • G. Stochel
  • L. Fiedor

  - JOURNAL OF MEDICINAL CHEMISTRY - Year 2008

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• The pharmacokinetics of propofol in ICU patients undergoing long-term sedation

  Publication

  • P. Smuszkiewicz
  • P. Wiczling
  • K. Przybyłowski
  • A. Borsuk
  • I. Trojanowska
  • M. Paterska
  • J. Matysiak
  • Z. Kokot
  • E. Grześkowiak
  • A. Bienert

  - BIOPHARMACEUTICS & DRUG DISPOSITION - Year 2016

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• Pharmacokinetics and pharmacodynamics of propofol in children undergoing different types of surgeries

  Publication

  • A. Bartkowska-Śniatkowska
  • A. Bienert
  • P. Wiczling
  • M. Owczarek
  • J. Rosada-Kurasińska
  • M. Grześkowiak
  • J. Matysiak
  • Z. Kokot
  • R. Kaliszan
  • E. Grześkowiak

  - Pharmacological Reports - Year 2014

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• Pharmacokinetics and pharmacodynamics of propofol in patients undergoing abdominal aortic surgery

  Publication

  • P. Wiczling
  • A. Bienert
  • P. Sobczyński
  • R. Hartmann-Sobczyńska
  • K. Bieda
  • A. Marcinkowska
  • M. Malatyńska
  • R. Kaliszan
  • E. Grześkowiak

  - Pharmacological Reports - Year 2012

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• Population pharmacokinetics of hydroxyurea for children and adolescents with sickle cell disease

  Publication

  • P. Wiczling
  • R. Liem
  • J. Panepinto
  • U. Garg
  • S. Abdel-Rahman
  • G. Kearns
  • K. Neville

  - JOURNAL OF CLINICAL PHARMACOLOGY - Year 2014

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• Pharmacokinetics and pharmacodynamics of propofol in cancer patients undergoing major lung surgery

  Publication

  • K. Przybyłowski
  • J. Tyczka
  • D. Szczesny
  • A. Bienert
  • P. Wiczling
  • K. Kut
  • E. Plenzler
  • R. Kaliszan
  • E. Grześkowiak

  - JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS - Year 2015

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• Pharmacokinetics and bioequivalence of a liquid formulation of hydroxyurea in children with sickle cell anemia

  Publication

  • J. Estepp
  • C. Melloni
  • C. Thornburg
  • P. Wiczling
  • Z. Rogers
  • J. Rothman
  • N. Green
  • R. Liem
  • A. Brandow
  • S. Crary... and 6 others

  - JOURNAL OF CLINICAL PHARMACOLOGY - Year 2016

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• Pharmacokinetics of sufentanil during long-term infusion in critically ill pediatric patients

  Publication

  • A. Bartkowska-Śniatkowska
  • A. Bienert
  • P. Wiczling
  • J. Rosada-Kurasińska
  • M. Zielińska
  • J. Warzybok
  • A. Borsuk
  • D. Tibboel
  • R. Kaliszan
  • E. Grześkowiak

  - JOURNAL OF CLINICAL PHARMACOLOGY - Year 2016

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• Flip-Flop Phenomenon in Epidural Sufentanil Pharmacokinetics: A Population Study in Children and Infants

  Publication

  • A. Borsuk
  • B. Wołoszczuk-Gębicka
  • A. Bartkowska-Śniatkowska
  • J. Rosada-Kurasińska
  • A. Bienert
  • P. Wiczling

  - JOURNAL OF CLINICAL PHARMACOLOGY - Year 2017

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• EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS

  Journals

  ISSN: 0378-7966 , eISSN: 2107-0180

• Pharmacokinetics and Antibody Responses to the CD3 Antibody Otelixizumab Used in the Treatment of Type 1 Diabetes

  Publication

  • G. Hale
  • P. Rebello
  • I. Al
  • E. Bolam
  • P. Wiczling
  • W. Jusko
  • E. Vandemeulebroucke
  • B. Keymeulen
  • C. Mathieu
  • A. Ziegler... and 3 others

  - JOURNAL OF CLINICAL PHARMACOLOGY - Year 2010

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• Potential pitfalls of propofol target controlled infusion delivery related to its pharmacokinetics and pharmacodynamics

  Publication

  • A. Bienert
  • P. Wiczling
  • E. Grześkowiak
  • J. Cywiński
  • K. Kusza

  - Pharmacological Reports - Year 2012

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• Melatonin and clonidine premedication has similar impact on the pharmacokinetics and pharmacodynamics of propofol target controlled-infusions

  Publication

  • A. Bienert
  • K. Wawrzyniak
  • P. Wiczling
  • K. Przybyłowski
  • Z. Kokot
  • J. Matysiak
  • A. Pachutko
  • M. Józefowicz
  • K. Kusza
  • E. Grześkowiak

  - JOURNAL OF CLINICAL PHARMACOLOGY - Year 2015

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• Review of Clinical Pharmacology and Pharmacokinetics, International Edition

  Journals

  ISSN: 1011-6583

• The pharmacokinetics of dexmedetomidine during long-term infusion in critically ill pediatric patients. A Bayesian approach with informative priors

  Publication

  • P. Wiczling
  • A. Bartkowska-Śniatkowska
  • O. Szerkus
  • D. Siluk
  • J. Rosada-Kurasińska
  • J. Warzybok
  • A. Borsuk
  • R. Kaliszan
  • E. Grześkowiak
  • A. Bienert

  - JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS - Year 2016

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• Population analysis to assess the influence of age and body weight on pharmacokinetics and pharmacodynamics of dexmedetomidine in New Zealand White rabbits

  Publication

  • J. Warzybok
  • A. Bienert
  • A. Borsuk‐De
  • W. Płotek
  • K. Kulińska
  • K. Czerniak
  • H. Billert
  • A. Klupczyńska
  • J. Matysiak
  • E. Grześkowiak
  • P. Wiczling

  - BIOPHARMACEUTICS & DRUG DISPOSITION - Year 2020

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• Pharmacokinetics and pharmacodynamics of propofol and fentanyl in patients undergoing abdominal aortic surgery - a study of pharmacodynamic drug-drug interactions

  Publication

  • P. Wiczling
  • K. Bieda
  • K. Przybyłowski
  • R. Hartmann-Sobczyńska
  • A. Borsuk
  • J. Matysiak
  • Z. Kokot
  • P. Sobczyński
  • E. Grześkowiak
  • A. Bienert

  - BIOPHARMACEUTICS & DRUG DISPOSITION - Year 2016

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• CLINICAL PHARMACOKINETICS

  Journals

  ISSN: 0312-5963 , eISSN: 1179-1926

• Population pharmacokinetics of standard-dose meropenem in critically ill patients on continuous renal replacement therapy: a prospective observational trial

  Publication

  • D. Onichimowski
  • A. Będźkowska
  • H. Ziółkowski
  • J. Jaroszewski
  • M. Borys
  • M. Czuczwar
  • P. Wiczling

  - Pharmacological Reports - Year 2020

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• Pharmacokinetics and Pharmacodynamics of a Chimeric/Humanized Anti-CD3 Monoclonal Antibody, Otelixizumab (TRX4), in Subjects With Psoriasis and With Type 1 Diabetes Mellitus

  Publication

  • P. Wiczling
  • M. Rosenzweig
  • L. Vaickus
  • W. Jusko

  - JOURNAL OF CLINICAL PHARMACOLOGY - Year 2010

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• <p>In vivo Studies on Pharmacokinetics, Toxicity and Immunogenicity of Polyelectrolyte Nanocapsules Functionalized with Two Different Polymers: Poly-L-Glutamic Acid or PEG</p>

  Publication

  • A. Karabasz
  • K. Szczepanowicz
  • A. Cierniak
  • R. Mezyk-Kopec
  • G. Dyduch
  • M. Szczęch
  • J. Bereta
  • M. Bzowska

  - International Journal of Nanomedicine - Year 2019

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• Efficacy, pharmacokinetics, and safety of the biosimilar CT-P10 compared with rituximab in patients with previously untreated advanced-stage follicular lymphoma: a randomised, double-blind, parallel-group, non-inferiority phase 3 trial

  Publication

  • W. Kim
  • C. Buske
  • M. Ogura
  • W. Jurczak
  • J. Sancho
  • E. Zhavrid
  • J. Kim
  • J. Hernández-Rivas
  • A. Prokharau
  • M. Vasilica... and 7 others

  - Lancet Haematology - Year 2017

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• Population Pharmacokinetic Modelling of Filgrastim in Healthy Adults following Intravenous and Subcutaneous Administrations

  Publication

  • P. Wiczling
  • P. Lowe
  • E. Pigeolet
  • F. Lüdicke
  • S. Balser
  • W. Krzyzanski
  • P. Wiczling

  - CLINICAL PHARMACOKINETICS - Year 2009

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• Age-structured population model of cell survival

  Publication

  • W. Krzyzanski
  • P. Wiczling
  • A. Gebre
  • P. Wiczling

  - JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS - Year 2017

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• Assessing circadian rhythms in propofol PK and PD during prolonged infusion in ICU patients

  Publication

  • A. Bienert
  • K. Kusza
  • K. Wawrzyniak
  • E. Grześkowiak
  • Z. Kokot
  • J. Matysiak
  • T. Grabowski
  • A. Wolc
  • P. Wiczling
  • M. Regulski

  - JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS - Year 2010

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• Review on Current Status of Echinocandins Use

  Publication

  • M. Mroczyńska-Szeląg
  • A. Brillowska-Dąbrowska

  - Antibiotics-Basel - Year 2020

  Fungal infections are rising all over the world every year. There are only five medical compound classes for treatment: triazoles, echinocandins, polyenes, flucytosine and allylamine. Currently, echinocandins are the most important compounds, because of their wide activity spectrum and much lower sides effects that may occur during therapy with other drugs. Echinocandins are secondary metabolites of fungi, which can inhibit the...

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• Michal Markuszewski prof. dr hab.

  People

• Mohamed Abouzid

  People

  Passionate about clinical sciences and epigenetics