Search results for: AMIKACIN SULFATE

• Antibacterial Porous Systems Based on Polylactide Loaded with Amikacin

  Publication

  • M. Glinka
  • K. Filatova
  • J. Kucińska-Lipka
  • T. Šopík
  • E. Domincová Bergerová
  • V. Mikulcová
  • A. Wasik
  • V. Sedlařík

  - MOLECULES - Year 2022

  Three porous matrices based on poly(lactic acid) are proposed herein for the controlled release of amikacin. The materials were fabricated by the method of spraying a surface liquid. Description is given as to the possibility of employing a modifier, such as a silica nanocarrier, for prolonging the release of amikacin, in addition to using chitosan to improve the properties of the materials, e.g., stability and sorption capacity....

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• APPLIED SURFACE SCIENCE

  Journals

  ISSN: 0169-4332 , eISSN: 1873-5584

• Encapsulation of Amikacin into Microparticles Based on Low-Molecular-Weight Poly(lactic acid) and Poly(lactic acid-co-polyethylene glycol)

  Publication

  • M. Glinka
  • K. Filatova
  • J. Kucińska-Lipka
  • E. D. Bergerova
  • A. Wasik
  • V. Sedlařík

  - MOLECULAR PHARMACEUTICS - Year 2021

  The aim of this study was to fabricate novel microparticles (MPs) for efficient and long-term delivery of amikacin (AMI). The emulsification method proposed for encapsulating AMI employed low-molecular-weight poly(lactic acid) (PLA) and poly(lactic acid-co-polyethylene glycol) (PLA−PEG), both supplemented with poly(vinyl alcohol) (PVA). The diameters of the particles obtained were determined as less than 30 μm. Based on an in-vitro...

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• SURFACE & COATINGS TECHNOLOGY

  Journals

  ISSN: 0257-8972

• Determination of amikacin and ciprofloxacin by liquid chromatography with pre-column derivatization to evaluate sustained delivery of antibiotics from Drug-Eluting Biopsy Needle

  Publication

  • M. Glinka
  • J. Kucińska-Lipka
  • A. Wasik

  - Year 2018

  Determination of chosen antibacterial antibiotics: amikacin and ciprofloxacin was carried out by HPLC-UV after derivatization with 9-fluorenylmethyl chloroformate and in their native form by HPLC-MS/MS. Developed methods have been applied to control the kinetics of antibiotic release from polymer-based controlled drug delivery system.

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• Surface Innovations

  Journals

  ISSN: 2050-6252 , eISSN: 2050-6260

• Ocular Surface

  Journals

  ISSN: 1542-0124 , eISSN: 1937-5913

• Surface Technology

  Journals

  eISSN: 1001-3660

• Synthesis and biological evaluation of fluorinated 3-phenylcoumarin-7-O-sulfamate derivatives as steroid sulfatase inhibitors

  Publication

  • S. Demkowicz
  • M. Daśko
  • W. Kozak
  • K. Krawczyk
  • D. Witt
  • M. Masłyk
  • K. Kubiński
  • J. Rachoń

  - Chemical Biology & Drug Design - Year 2016

  In the present work, we report the initial results of our study on a series of 3-phenylcoumarin sulfamate-based compounds containing C-F bonds as a novel inhibitors of steroid sulfatase (STS). The new compounds are potent STS inhibitors, possessing more than 10 times higher inhibitory potency than coumarin-7-O-sulfamate. In the course of our investigation, compounds 2b and 2c demonstrated the highest inhibitory effect in the enzymatic...

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• SURFACE SCIENCE

  Journals

  ISSN: 0039-6028 , eISSN: 1879-2758