Search results for: B-LAKTAMY

• PHYSICAL REVIEW B

  Journals

  ISSN: 2469-9950 , eISSN: 2469-9969

• One-Step Synthesis of b-Lactams with Retro-Amide Side Chain

  Publication

  • K. Janikowska
  • N. Pawelska
  • S. Makowiec

  - SYNTHESIS-STUTTGART - Year 2011

  Abstract: A one pot synthesis for preparation of 1,4-disubstituted-2-oxo-azetidine-3-carboxylic acid amides was developed. 5-(α-N-substituted-amino-α'-hydroxy)methylene Meldrum's acids act as a source of ketenes that react with aldimines in boiling toluene to give b-lactams with retro-amid side chain.

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• A new approach to the stereoselective synthesis of trans-3-carbamoyl-b-lactam moieties†

  Publication

  • Z. Anna
  • N. Ewelina
  • S. Makowiec

  - NEW JOURNAL OF CHEMISTRY - Year 2017

  One-pot synthesis of optically active 1,4-disubstituted-3-carbamoyl-azetidinones from 5-[(N-arylamino)- (hydroxyl)methylene]-2,2-dimethyl-1,3-dioxa-4,6-diones and chiral aldimines is achieved via thermal generation of carbamoyl ketenes and subsequent [2+2] cycloaddition. Three possible chiral induction approaches were tested and (R)-(+)-1-phenylethylamine was confirmed as the best chiral auxiliary. Among the four possible diastereoisomers,...

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• JOURNAL OF PHYSICAL CHEMISTRY B

  Journals

  ISSN: 1520-6106 , eISSN: 1520-5207

• Synthesis of 3-Carbamoyl b-Lactams via Manganese(III)-Promoted Cyclization of N-Alkenylmalonamides

  Publication

  • P. Punda
  • Ł. Ponikiewski
  • S. Makowiec

  - HELVETICA CHIMICA ACTA - Year 2013

  Manganese(III)-promoted cyclization of N-alkenylmalonamides (¼N-alkenylpropanediamides) gave 3-(aryl/(alkylamino)carbonyl) b-lactams as well as 3-(aryl/(alkylamino)thiocarbonyl) b-lactams. The relative configuration of the obtained products was unambiguously determined by X-ray crystallography. The proposed method is very useful for the one-pot synthesis of a number of 3-(aryl/ (alkylamino)carbonyl) b-lactams, especially those...

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• SENSORS AND ACTUATORS B-CHEMICAL

  Journals

  ISSN: 0925-4005

• APPLIED CATALYSIS B-ENVIRONMENTAL

  Journals

  ISSN: 0926-3373 , eISSN: 1873-3883

• COMPOSITES PART B-ENGINEERING

  Journals

  ISSN: 1359-8368 , eISSN: 1879-1069

• <b><i>CTLA4</i></b> and <b><i>CD28</i></b> Gene Polymorphisms with Respect to Affective Symptom Domain in Schizophrenia

  Publication

  • D. Frydecka
  • J. Beszlej
  • E. Pawlak-Adamska
  • B. Misiak
  • L. Karabon
  • A. Tomkiewicz
  • A. Partyka
  • A. Jonkisz
  • M. Szewczuk-Boguslawska
  • M. Zawadzki
  • A. Kiejna

  - NEUROPSYCHOBIOLOGY - Year 2015

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• Węzły grupy B

  Publication

  • R. Krystek

  - Year 2008

  Węzły grupy B są budowane na przecięciach dróg, z których jedna - z definicji - nie może mieć punktów kolizji, na drugiej natomiast są one dopuszczalne. Węzeł taki oznacza zazwyczaj połączenie drogi ruchu szybkiego z drogami podrzędnymi. Oczywiście, nawet na przecięciu dróg ogólnodostępnych może być zastosowany węzeł grupy A - czyli węzeł całkowicie bezkolizyjny, o ile natężenia i ranga krzyżujących się dróg uzasadniają przyjecie...