Search results for: METABOLITE PURIFICATION

• SEPARATION AND PURIFICATION TECHNOLOGY

  Journals

  ISSN: 1383-5866 , eISSN: 1873-3794

• PROTEIN EXPRESSION AND PURIFICATION

  Journals

  ISSN: 1046-5928 , eISSN: 1096-0279

• Metabolites

  Journals

  ISSN: 2218-1989

• BLOOD PURIFICATION

  Journals

  ISSN: 0253-5068 , eISSN: 1421-9735

• Urine metabolic fingerprinting using LC–MS and GC–MS reveals metabolite changes in prostate cancer: A pilot study

  Publication

  • W. Struck-Lewicka
  • M. Kordalewska
  • R. Bujak
  • A. Yumba
  • M. Markuszewski
  • J. Jacyna
  • M. Matuszewski
  • R. Kaliszan
  • M. Markuszewski

  - Journal of Pharmaceutical and Biomedical Analysis - Year 2015

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• Diminshed toxicity of C-1748, 4-methyl-9-hydroxyethylamino-1-nitroacridine, compared with its demethyl analog, C-857, corresponds to its resistance to metabolism in HepG2 cells

  Publication

  • A. Wiśniewska
  • M. Niemira
  • K. Jagiełło
  • A. Potęga
  • M. Świst
  • C. Henderson
  • A. Skwarska
  • E. Augustin
  • J. Konopa
  • Z. Mazerska

  - BIOCHEMICAL PHARMACOLOGY - Year 2012

  The narrow "therapeutic window" of anti-tumour therapy may be the result of drug metabolism leading to the activation or detoxification of antitumour agents. The aim of this work is to examine (i) whether the diminished toxicity of a potent antitumour drug, C-1748, 9-(2'-hydroxyethylamino)-4-methyl-1-nitroacridine, compared with its 4-demethyl analogue, C-857, results from the differences between the metabolic pathways for the...

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• Genetic response to metabolic fluctuations: correlation between central carbon metabolism and DNA replication in Escherichia coli

  Publication

  • M. Maciąg
  • D. Nowicki
  • L. Janniere
  • A. Szalewska-Pałasz
  • G. Węgrzyn

  - Microbial Cell Factories - Year 2011

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• Electrochemical simulation of metabolism for antitumor-active imidazoacridinone C-1311 and in silico prediction of drug metabolic reactions

  Publication

  • A. Potęga
  • D. Żelaszczyk
  • Z. Mazerska

  - JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS - Year 2019

  The metabolism of antitumor-active 5-diethylaminoethylamino-8-hydroxyimidazoacridinone (C-1311) has been investigated widely over the last decade but some aspects of molecular mechanisms of its metabolic transformation are still not explained. In the current work, we have reported a direct and rapid analytical tool for better prediction of C-1311 metabolism which is based on electrochemistry (EC) coupled on-line with electrospray...

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• New plasma preparation approach to enrich metabolome coverage in untargeted metabolomics: plasma protein bound hydrophobic metabolite release with proteinase K

  Publication

  • R. Wawrzyniak
  • A. Kosnowska
  • S. Macioszek
  • R. Bartoszewski
  • M. Jan

  - Scientific Reports - Year 2018

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• The production and properties of the secondary metabolites in selected car-nivorous plants = Produkcja i właściwości metabolitów wtórnych wybranych roślin owadożernych

  Publication

  • A. Dziabas
  • A. Królicka
  • R. Kartanowicz
  • M. A. Kamiński
  • E. Łojkowska

  - Year 2003

  Pięć gatunków roślin owadożernych (Drosera aliciae, D. capensis, D. ramenta-cea, D. rotundifolia oraz Sarracenia psittacina ) zostało zbadanych pod ką-tem produkcji i właściwości metabolitów wtórnych między innymi flawonoidów inaftochinonów. W tym celu rośliny poddano elicytacji in vitro przy użyciuelicytorów abiotycznych - TYTANIT, kwas jasmonowy, BION oraz biotycznych -chityna i Enterobacter sakazaki. Badane związki ekstrahowano...