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Search results for: LANDSCAPE ECOLOGY
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Expression profiles and genomic organisation of group A protein phosphatase 2C genes inBrassica oleracea
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Expression profiles of vault components MVP, TEP1 and vPARP and their correlation to other multidrug resistance proteins in ovarian cancer
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Kinetic flux vector splitting scheme for solving non-reactive multi-component flows
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Expression of intermediate filaments of podocytes within nephrotic syndrome glomerulopathies in children
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Synthesis and antimicrobial activity of truncated fragments and analogs of citropin 1.1: The solution structure of the SDS micelle-bound citropin-like peptides
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The Arctic mutation alters helix length and type in the 11–28 β-amyloid peptide monomer—CD, NMR and MD studies in an SDS micelle
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Multivariate evaluation by quality indicators of no-tillage system in Argiudolls of rolling pampa (Argentina)
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Overactive bladder treatment: application of methylene blue to improve the injection technique of onabotulinum toxin A
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The Relationship of Purpose in Life and Hope in Shaping Happiness Among Patients with Cancer in Poland
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Impact of Housing System on Health and Rearing of Calves Based on Examination of Nasal Cavity Swabs
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Increased water content in bacterial cellulose synthesized under rotating magnetic fields
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Molecular differences in mitochondrial DNA genomes of dogs with malignant mammary tumours
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Chirurgiczne leczenie chorych na raka pęcherzyka żółciowego: doświadczenia własne na podstawie 16 przypadków
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Stigmas of holoparasitic Phelipanche arenaria (Orobanchaceae) – a suitable ephemeric flower habitat for development unique microbiome
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Belinostat in Patients With Relapsed or Refractory Peripheral T-Cell Lymphoma: Results of the Pivotal Phase II BELIEF (CLN-19) Study
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Ibrutinib as Treatment for Patients With Relapsed/Refractory Follicular Lymphoma: Results From the Open-Label, Multicenter, Phase II DAWN Study
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Venetoclax for Patients With Chronic Lymphocytic Leukemia With 17p Deletion: Results From the Full Population of a Phase II Pivotal Trial
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Analysis of the unique structural and physicochemical properties of the DraD/AfaD invasin in the context of its belonging to the family of chaperone/usher type fimbrial subunits
PublicationInwazyna DraD kodowana przez operon dra posiada strukturę charakterystyczną dla białek podjednostkowych fimbrii typu chaperone-usher. Fold-Ig białka DraD posiada dwie charakterystyczne cechy wyróżniające je z pośród rodziny fimbrialnych białek podjednostkowych: 1) zaburzenie struktury beta-beczki w rejonie szczeliny akceptorowej objawiające się układem wiązań wodorowych głównego łańcucha polipeptydowego oraz 2) nietypowo usytuowany...
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Comet assay-based methods for measuring DNA repair in vitro; estimates of inter- and intra-individual variation.
PublicationZdolność do naprawy uszkodzeń DNA jest jednym z najważniejszych wyznaczników podatności na choroby nowotworowe. Dlatego też użytecznym staje się możliwość pomiaru stopnia naprawy DNA w próbkach materiału badawczego pobranego od ochotników. Celem pracy było, po pierwsze, opracowanie w warunkach in vitro prostej metody (z wykorzystaniem techniki testu kometowego), w której naprawa DNA odbywa się poprzez wycinanie nukleotydów (NER)....
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Pre-clinical evaluation of 1-nitroacridine derived chemotherapeutic agent that has preferential cytotoxic activity towards prostate cancer
PublicationPraca zawiera wyniki badań przedklinicznych pochodnej 1-nitroakrydyny C-1748 wobec komórek ludzkiego raka prostaty CaP in vitro, jak i przeszczepialnego na zwierzęta. W oparciu o fosforylację histonu H2AX jako markera podwójnych cięć DNA wykazano, że C-1748 jest bardziej aktywny w komórkach CaP niż HL60. Zidentyfikowano poza tym receptor androgenny (AR) jako cel molekularny badanego związku. W doświadczeniach na zwierzętach stwierdzono...
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Inhibition of HIV‐1 or bacterial activation of macrophages by products of HIV‐1‐resistant human cells
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Enrichment of Bi-Be-Mo-Cd-Pb-Nb-Ga, REEs and Y in the Permian coals of the Huainan Coalfield, Anhui, China
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Reply to “Enrichment of Bi-Be-Mo-Cd-Pb-Nb-Ga, REEs and Y in the Permian coals of the Huainan Coalfield, Anhui, China: Discussion”
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Emerging developments in ASEAN–China relations in regional production linkages
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Tipping point in plant–fungal interactions under severe drought causes abrupt rise in peatland ecosystem respiration
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Ericoid shrub encroachment shifts aboveground–belowground linkages in three peatlands across Europe and Western Siberia
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A New Era Is Beginning in Central and Eastern Europe: Information and Communication Technology Services Exceed Manufacturing in the Global Production Chain
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Radiation dose distributions in three dimensions from tomographic optical density scanning of polymer gels: I. Development of an optical scanner
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Generalization of Phylogenetic Matching Metrics with Experimental Tests of Practical Advantages
PublicationThe ability to quantify a dissimilarity of different phylogenetic trees is required in various types of phylogenetic studies, for example, such metrics are used to assess the quality of phylogeny construction methods and to define optimization criteria in supertree building algorithms. In this article, starting from the already described concept of matching metrics, we define three new metrics for rooted phylogenetic trees. One...
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Molecular mechanism of proton-coupled ligand translocation by the bacterial efflux pump EmrE
PublicationThe current surge in bacterial multi-drug resistance (MDR) is one of the largest challenges to public health, threatening to render ineffective many therapies we rely on for treatment of serious infections. Understanding different factors that contribute to MDR is hence crucial from the global “one health” perspective. In this contribution, we focus on the prototypical broad-selectivity proton-coupled antiporter EmrE, one of the...
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Molecularly targeted nanoparticles: an emerging tool for evaluation of expression of the receptor for advanced glycation end products in a murine model of peripheral artery disease
PublicationAbstract Background: Molecular imaging with molecularly targeted probes is a powerful tool for studying the spatio-temporal interactions between complex biological processes. The pivotal role of the receptor for advanced glycation end products (RAGE) in numerous pathological processes, aroused the demand for RAGE targeted imaging in various diseases. In the study, we evaluated the use of a diagnostic imaging agent for RAGE quantification...
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Can architecture be 11-dimensional? The nature of space in the architecture of the digital world era
PublicationThis research aims to explore the development of architectural theories about ‘architectural dimensions’ and look at architecture as a multidimensional space. It is important to understand that with today's development of virtual reality technology and through the combination of theories of physics and architecture, a new possibility of creating space has emerged. The arguments are made through inductive reasoning and grounded...
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Two bacterial small heat shock proteins, IbpA and IbpB, form a functional heterodimer
PublicationSmall heat shock proteins (sHsps) are a conserved class of ATP-independent chaperones which in stress conditions bind to unfolded protein substrates and prevent their irreversible aggregation. Substrates trapped in sHsps-containing aggregates are efficiently refolded into native structures by ATP-dependent Hsp70 and Hsp100 chaperones. Most γ-proteobacteria possess a single sHsp (IbpA), while in a subset of Enterobacterales, as...
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Determinants of the primary stability of cementless acetabular cup implants: A 3D finite element study
PublicationPrimary stability of cementless implants is crucial for the surgical success and long–term stability. However, primary stability is difficult to quantify in vivo and the biomechanical phenomena occurring during the press–fit insertion of an acetabular cup (AC) implant are still poorly understood. The aim of this study is to investigate the influence of the cortical and trabecular bone Young's moduli Ec and Et, the interference...
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Human UDP-Glucuronosyltransferases: Effects of altered expression in breast and pancreatic cancer cell lines.
PublicationIncreased aerobic glycolysis and de novo lipid biosynthesis are common characteristics of invasive cancers. UDP-glucuronosyltransferases (UGTs) are phase II drug metabolizing enzymes that in normal cells possess the ability to glucuronidate these lipids and speed their excretion; however, de-regulation of these enzymes in cancer cells can lead to an accumulation of bioactive lipids, which further fuels cancer progression. We hypothesize...
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Scavenging is no magic
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Magnetic resonance imaging of radiation dose distributions using a polymer-gel dosimeter
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Radiation dose distributions in three dimensions from tomographic optical density scanning of polymer gels: II. Optical properties of the BANG polymer gel
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The use of gel dosimetry to measure the 3D dose distribution of a90Sr/90Y intravascular brachytherapy seed
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Jerusalem artichoke (Helianthus tuberosus L.) as a medicinal plant and its natural products
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Two-dimensional gel-based serum protein profile of growing piglets
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Anatomical and morphological study of the kidneys of the breeding emu(Dromaius novaehollandiae)
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Immunohistochemical identification of aquaporin 2 in the kidneys of wild boars (Sus scrofa)
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Cold-modulated leaf compounds in winter triticale DH lines tolerant to freezing and
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Transcriptome profiling and environmental linkage to salinity across Salicornia europaea vegetation
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Correlation of Polymorphism of AQP7 Gene with the Sperm Cells Quality Traits of the Polish Holstein Friesian Bulls
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Salt stress vs. salt shock - the case of sugar beet and its halophytic ancestor
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Buserelin Acetate Reduces Mortality and DNA Defragmentation of Bovine Sperm Cells Exposed to Oxidative Stress
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C90 PATHOLOGICAL CHARACTERISTICS OF UROTHELIAL CELL CARCINOMA OF THE BLADDER IN YOUNG PATIENTS
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The Impact of Selected Breeding and Environmental Factors on the Efficiency of Rearing Calves
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