Search results for: METABOLIZM KSENOBIOTYKÓW
-
Ascorbate and glutathione metabolism in embryo axes and cotyledons of germinating lupine seeds
Publication -
The II phase metabolism of endogenous and exogenous compounds, including antitumor chemotherapeutics
PublicationThe II phase metabolism, it is a set of metabolism and excretion pathways of endogenous as well as exogenous compounds including xenobiotics. UDP-glucuronyltransferases (UGTs; EC 2.4.1.17) are the most crucial representatives of II phase enzymes, which are responsible for the transformation of bilirubine and bile acids, steroids and thyroid hormones and lipids. Exogenous compounds, including drugs, carcinogens, environmental pollutants...
-
DIABETES OBESITY & METABOLISM
Journals -
Journal of Endocrinology and Metabolism
Journals -
Nutritional Therapy & Metabolism
Journals -
Journal of Nutrition and Metabolism
Journals -
Archives of Endocrinology Metabolism
Journals -
Cardiovascular Endocrinology & Metabolism
Journals -
Diabetes & Metabolism Journal
Journals -
Drug Metabolism and Pharmacokinetics
Journals -
DIABETES NUTRITION & METABOLISM
Journals -
Journal of Diabetes & Metabolism
Journals -
Drug Metabolism Letters
Journals -
Human Nutrition and Metabolism
Journals -
MOLECULAR GENETICS AND METABOLISM
Journals -
METABOLISM-CLINICAL AND EXPERIMENTAL
Journals -
Obesity and Metabolism-Milan
Journals -
Endocrinology, Diabetes and Metabolism
Journals -
Journal of Bone Metabolism
Journals -
Żywienie Człowieka i Metabolizm
Journals -
METABOLIC ENGINEERING
Journals -
ClaR—a novel key regulator of cellobiose and lactose metabolism in Lactococcus lactis IL1403
Publication -
Uptake, tissue distribution, and metabolism of malachite green in the channel catfish (Ictalurus punctatus)
Publication -
Metabolism of Tryptophan and Depressive Symptoms Six Months after Interferon- alfa Treatment
Publication -
Effects of Single and Repeated Footshock on Dopamine Release and Metabolism in the Brains of Fischer Rats
Publication -
Research Trends of Vitamin D Metabolism Gene Polymorphisms Based on a Bibliometric Investigation
Publication -
Erratum to: Activities of genes controlling sphingolipid metabolism in human fibroblasts treated with flavonoids
Publication -
The Phytoestrogen Genistein Modulates Lysosomal Metabolism and Transcription Factor EB (TFEB) Activation
Publication -
Caffeine Inhibits Differentiation Of Lung Cancer Stem Cells By Modulating Their Respiratory Metabolism
PublicationIt is ell established that many tumor types contain a fraction of cells, with stem cell-like properties, called cancer stem cells (CSCs), that are resistant to apoptosis induced by therapeutic agents. The presence of CSCs may explain why a standard anticancer treatment, that eliminates only differentiated cancer cells, does not lead to cancer cure.We previously showed the existence of caffeine-sensitive mechanism that controls...
-
Cytochromes P-450: specyfic enzymes involved in metabolism of endogenous substances and xenobiotics
PublicationCytochromy P-450 to grupa enzymów hemoproteinowych występujących w prawie wszystkich organizmach żywych. Substratami tych enzymów są zarówno substancje endogenne jak i ksenobiotyki, włączając w to leki, dodatki do żywności oraz zanieczyszczenia środowiska. W pracy omówiono rolę polimorfizmu oraz indukcji P-450 w metabolizmie leków przeciwnowotworowych.
-
Role of omentin and vaspin in metabolic diseases in association with psoriasis
Publication -
Modulation of mRNA and protein levels of CYP1A1, 1A2, and 1B1 in nontumorigenic breast epithelial cells (MCF10A) by cabbage juice and its active components
PublicationZbadano wpływ soków z kapusty oraz występujących w nich pochodnych indolowych i sulforafanu na poziom ekspresji enzymów odpowiedzialnych za metabolizm ksenobiotyków w tym estrogenów. Wykazano, że soki z kapusty i izolowane substancje mają podobny wpływ na poziom mRNA i białek enzymatycznych.
-
Metaboliczny potencjał energetyczny miast
PublicationTekst przedstawia koncepcje przepływów energii w strukturach zurbanizowanych. Zaprezentowano kolejno: metabolizm jako próbę oznaczenia zmiany, cechy anaboliczne i kataboliczne w dynamice miasta, nowe zwiastuny metabolizmu, rozlewanie i kurczenie się miast oraz "chirurgów" metabolizmu polskich miast.
-
Glukuronidacja leków przeciwnowotworowych – detoksyfikacja, mechanizm oporności czy sposób na formę proleku?*
PublicationKsenobiotyki podlegają w organizmie biotransformacji I i II fazy, której celem jest ich detoksyfikacja i ułatwienie wydalania. UDP-glukuronylotransferazy (UGT) – enzymy należące do II fazy metabolizmu katalizują przyłączenie kwasu glukuronowego do lipofilowego substratu zawierającego nukleofilową grupę funkcyjną. Nadrodzina UGT składa się z izoenzymów o różnej swoistości substratowej oraz odmiennym profilu ekspresji w poszczególnych tkankach....
-
Skin microbiota metabolism of natural products from comfrey root (Symphytum officinale L.)
Publication -
Platelets in fetal growth restriction: role of reactive oxygen species, oxygen metabolism, and aggregation.
PublicationFetal growth restriction (FGR) is mainly caused by failure of the uteroplacental unit. Theexact pathogenesis remains unclear. The cause is thought to be related to abnormal platelet activation,which may...
-
Characterization of In Vitro and In Vivo Metabolism of Antazoline Using Liquid Chromatography-Tandem Mass Spectrometry
Publication -
The role of cytochrome P450 reductase (CPR) in metabolism of potent nitroacridine antitumor, C-1748
PublicationCelem pracy było poznanie molekularnego mechanizmu działania pochodnych 9-amino-1-nitroakrydyny. Zbadano przemiany enzymatyczne tych związków w różnych układach enzymatycznych: I. Szczurza frakcja mikrosomalna z reduktazą cytochromu P450. II. Rekombinantowe izoenzymy cytochromu P450 z wysokim i niskim poziomem reduktazy cytochromu P450. III. Frakcje mikrosomalne dzikiego typu oraz pozbawione genu kodującego reduktazę cytochromu...
-
Interspecific allelopathy in cyanobacteria: Cylindrospermopsin and Cylindrospermopsis raciborskii effect on the growth and metabolism of Microcystis aeruginosa
Publication -
Glucose metabolism disorders in patients with non-functioning adrenal adenomas — single-centre experience
PublicationIntroduction: The presence of glucose metabolism disorders and their possible correlation with degree of cortisol secretion were evaluated in patients with non-functioning adrenal incidentalomas (NFAIs). Material and methods: The study group consisted of 131 patients with hormonally inactive adrenal incidentalomas....
-
Correction: Corrigendum: Modulation of expression of genes involved in glycosaminoglycan metabolism and lysosome biogenesis by flavonoids
Publication -
Correction: Corrigendum: Modulation of expression of genes involved in glycosaminoglycan metabolism and lysosome biogenesis by flavonoids
Publication -
Flavonoid biosynthetic pathways in plants: Versatile targets for metabolic engineering
Publication -
The usefulness of fluorescence in detecting ischemia during bariatric and metabolic surgery
Publication -
A numerical scale to assess the outcomes of metabolic/bariatric surgery (NOMS)
Publication -
Carbon assimilation profiles of mucoralean fungi show their metabolic versatility
Publication -
Metabolic profiling of pteridines for determination of potential biomarkers in cancer diseases
Publication -
Significance of selected inflammatory factors in metabolic disorders in association with psoriasis
Publication -
The metabolic syndrome in hypertension: European society of hypertension position statement
Publication -
Electronic Cigarette Use and Metabolic Syndrome Development: A Critical Review
Publication