Fibrosis and cirrhosis of liver - Male, 53 - Tissue image [6220730015165611] - Open Research Data - MOST Wiedzy

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Fibrosis and cirrhosis of liver - Male, 53 - Tissue image [6220730015165611]

Opis

This is the histopathological image of LIVER AND INTRAHEPATIC BILE DUCTS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

The detailed information about the patient, sample, and diagnosis are as follows:

Patient:

Age: 53

Clinical description: Liver fibrosis. Congenital haemochromatosis.

Gender: Male

Diagnosis:

Classification: ICD-10_10-20

Classification code: Chapter XI - Diseases of the digestive system

Diagnosis: Fibrosis and cirrhosis of liver

Result of the histopathological examination: In the examined oligopyoptate (one partially fragmented section) fragments of the enlarged biliary spaces are usually present, containing a large number of inflammatory cells, mainly mononuclear. Within the above-mentioned enlarged spaces, there are features of pronounced fibrogenesis, characterized by intense portal and periportal fibrosis with the formation of portal-portal fibrous bridges, it is possible that also portal-central, with the presence of a single regenerative nodule. In some portal spaces accumulating elements of collagen connective tissue, there is a clear proliferation of bile ducts. Large groups of enlarged hepatocytes are observed, especially those located near the portal spaces, depositing iron in the form of haemosiderin, and stimulated Borowicz-Kupffer cells accumulating hemosiderin. In places, there are features of mixed steatosis of quite numerous hepatocytes, with a predominance of large droplets. The microscopic image of the examined material indicates the process of intense fibrosis of on the base of congenital haemochromatosis, although coexistence of another liver pathology cannot be ruled out.

Sample:

Material: FFPE

Collecting method: Surgical specimen

Topography: DIGESTIVE ORGANS

Organ: LIVER AND INTRAHEPATIC BILE DUCTS

Tissue: Liver

Type of staining: positive/HC

Staining: Masson-Goldner

Antibody: Not applicable

Technology:

Equipment: Pannoramic 250 3DHistech

Lens: 20x

Organization:

Source: Medical University Gdańsk

Plik z danymi badawczymi

a590d402-9352-443e-bf28-b82954c2d481
852.4 MB, S3 ETag , pobrań: 2
Hash pliku liczony jest ze wzoru
hexmd5(md5(part1)+md5(part2)+...)-{parts_count} gdzie pojedyncza część pliku jest wielkości 512 MB

Przykładowy skrypt do wyliczenia:
https://github.com/antespi/s3md5

Informacje szczegółowe o pliku

Licencja:
Creative Commons: by-nc-sa 4.0 otwiera się w nowej karcie
CC BY-NC-SA
Użycie niekomercyjne - Na tych samych warunkach
Dane surowe:
Dane zawarte w datasecie nie zostały w żaden sposób przetworzone.
Oprogramowanie:
CaseViewer 2.3

Informacje szczegółowe

Rok publikacji:
2022
Data zatwierdzenia:
2022-05-10
Data wytworzenia:
2022
Język danych badawczych:
angielski
Dyscypliny:
  • nauki medyczne (Dziedzina nauk medycznych i nauk o zdrowiu)
DOI:
Identyfikator DOI 10.34808/nn5v-be76 otwiera się w nowej karcie
Ethical papers:
NKBBN/421-306/2020
Weryfikacja:
Gdański Uniwersytet Medyczny

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