Development of an Analytical Protocol for Determination of Cyanide in Human Biological Samples Based on Application of Ion Chromatography with Pulsed Amperometric Detection - Publikacja - MOST Wiedzy

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Development of an Analytical Protocol for Determination of Cyanide in Human Biological Samples Based on Application of Ion Chromatography with Pulsed Amperometric Detection

Abstrakt

A simple and accurate ion chromatography (IC) method with pulsed amperometric detection (PAD) was proposed for the determination of cyanide ion in urine, sweat, and saliva samples. The sample pretreatment relies on alkaline digestion and application of Dionex OnGuard II H cartridge. Under the optimized conditions, the method showed good linearity in the range of 1–100 μg/L for urine, 5–100 μg/L for saliva, and 3–100 μg/L for sweat samples with determination coefficients . Low detection limits (LODs) in the range of 1.8 μg/L, 5.1 μg/L, and 5.8 μg/L for urine, saliva, and sweat samples, respectively, and good repeatability (CV < 3%, ) were obtained. The proposed method has been successfully applied to the analysis of human biological samples.

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Informacje szczegółowe

Kategoria:
Publikacja w czasopiśmie
Typ:
artykuł w czasopiśmie wyróżnionym w JCR
Opublikowano w:
Journal of Analytical Methods in Chemistry nr 2017, strony 1 - 7,
ISSN: 2090-8865
Język:
angielski
Rok wydania:
2017
Opis bibliograficzny:
Jaszczak-Wilke E., Ruman M., Narkowicz S., Namieśnik J., Polkowska Ż.: Development of an Analytical Protocol for Determination of Cyanide in Human Biological Samples Based on Application of Ion Chromatography with Pulsed Amperometric Detection// Journal of Analytical Methods in Chemistry. -Vol. 2017, (2017), s.1-7
DOI:
Cyfrowy identyfikator dokumentu elektronicznego (otwiera się w nowej karcie) 10.1155/2017/7157953
Źródła finansowania:
  • COST_FREE
Weryfikacja:
Politechnika Gdańska

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