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Exposure scenario and risk assessment of infants and newborns to bisphenols and their derivatives from diapers
Abstrakt
Newborns and infants are more sensitive to harmful compounds such as bisphenols and their derivatives because of their not fully developed detoxification mechanism. Exposure to these substances can lead to developmental problems and health consequences in adulthood. Since disposable baby diapers are used from the first days of life and remain in contact with the baby skin, it seems important to monitor the levels of endocrine disrupting chemicals (EDCs) in such products. Ultrasound assisted solvent microextraction of porous membrane-packed solid sample (UASE-PMSS) was used in sample preparation. Liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) was used at determination step. Bisphenol A was quantified with the highest frequency at 81 % of samples tested, ranging from 5.0 to 520 ng/g. BADGE⋅2HCl was also quantified in high concentrations (from 6.8 to 530 ng/g), but was found in only 15 % of the tested samples. The daily exposure dose (DED) of bisphenols was calculated. In addition health risk assessment was conducted using previous (4 μg/kg BW) and actual (0.2 ng/kg BW) values of tolerable daily intake (TDI) of bisphenol A recommended by European Food Safety Authority (EFSA).
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- Wersja publikacji
- Accepted albo Published Version
- DOI:
- Cyfrowy identyfikator dokumentu elektronicznego (otwiera się w nowej karcie) 10.1016/j.ecoenv.2023.115351
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Informacje szczegółowe
- Kategoria:
- Publikacja w czasopiśmie
- Typ:
- artykuły w czasopismach
- Opublikowano w:
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ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
nr 262,
ISSN: 0147-6513 - Język:
- angielski
- Rok wydania:
- 2023
- Opis bibliograficzny:
- Chabowska A., Jatkowska N., Kubica P., Płotka-Wasylka J.: Exposure scenario and risk assessment of infants and newborns to bisphenols and their derivatives from diapers// ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY -Vol. 262, (2023), s.115351-
- DOI:
- Cyfrowy identyfikator dokumentu elektronicznego (otwiera się w nowej karcie) 10.1016/j.ecoenv.2023.115351
- Źródła finansowania:
- Weryfikacja:
- Politechnika Gdańska
wyświetlono 56 razy
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