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Evaluating Gelatin-Based Films with Graphene Nanoparticles for Wound Healing Applications

Abstract

In this study, gelatin-based films containing graphene nanoparticles were obtained. Nanoparticles were taken from four chosen commercial graphene nanoplatelets with different surface areas, such as 150 m2/g, 300 m2/g, 500 m2/g, and 750 m2/g, obtained in different conditions. Their morphology was observed using SEM with STEM mode; porosity, Raman spectra and elemental analysis were checked; and biological properties, such as hemolysis and cytotoxicity, were evaluated. Then, the selected biocompatible nanoparticles were used as the gelatin film modification with 10% concentration. As a result of solvent evaporation, homogeneous thin films were obtained. The surface’s properties, mechanical strength, antioxidant activity, and water vapor permeation rate were examined to select the appropriate film for biomedical applications. We found that the addition of graphene nanoplatelets had a significant effect on the properties of materials, improving surface roughness, surface free energy, antioxidant activity, tensile strength, and Young’s modulus. For the most favorable candidate for wound dressing applications, we chose a gelatin film containing nanoparticles with a surface area of 500 m2/g.

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Authors (9)

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Details

Category:
Articles
Type:
artykuły w czasopismach
Published in:
Nanomaterials no. 13,
ISSN: 2079-4991
Language:
English
Publication year:
2023
Bibliographic description:
Kamedulski P., Wekwejt M., Zasada L., Ronowska A., Michno A., Chmielniak D., Binkowski P., Lukaszewicz J. P., Kaczmarek-Szczepańska B.: Evaluating Gelatin-Based Films with Graphene Nanoparticles for Wound Healing Applications// Nanomaterials -,iss. 23 (2023), s.3068-
DOI:
Digital Object Identifier (open in new tab) 10.3390/nano13233068
Verified by:
Gdańsk University of Technology

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