Jarosław Ruczyński - Publications - Bridge of Knowledge

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Year 2021
  • PTD4 Peptide Increases Neural Viability in an In Vitro Model of Acute Ischemic Stroke
    Publication
    • J. Mazuryk
    • I. Puchalska
    • K. Koziński
    • M. J. Ślusarz
    • J. Ruczyński
    • P. Rekowski
    • P. Rogujski
    • R. Płatek
    • M. B. Wiśniewska
    • A. Piotrowski... and 7 others

    - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - Year 2021

    Ischemic stroke is a disturbance in cerebral blood flow caused by brain tissue ischemia and hypoxia. We optimized a multifactorial in vitro model of acute ischemic stroke using rat primary neural cultures. This model was exploited to investigate the pro-viable activity of cell-penetrating peptides: arginine-rich Tat(49–57)-NH2 (R49KKRRQRRR57-amide) and its less basic analogue, PTD4 (Y47ARAAARQARA57-amide). Our model included glucose...

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Year 2019

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