Year 2015

• The compositional space of exhaled breath condensate and its link to the human breath volatilome

  Publication

  • F. Moritz
  • M. Janicka
  • A. Zygler
  • S. Forcisi
  • A. Kot-Wasik
  • J. Kot
  • I. Gebefüg
  • J. Namieśnik
  • P. Schmitt-Kopplin

  - Journal of Breath Research - Year 2015

  Breath analysis is commonly understood to target gaseous or volatile organic compounds (VOCs) for the characterization of different pathologies. Targeted analysis is most effective if a working hypothesis can be based on a plethora of data. The recently published volatilome builds an optimal basis for organizing powerful target sets. However, the origin and pathways of biosynthesis of many VOCs are not known, which complicates...

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Year 2013

• LC-MS/MS dtermination of isoprostanes in plasma samples collected from mice exposed to doxorubicin or tert-butyl hydroperoxide

  Publication

  • M. Janicka
  • A. Kot-Wasik
  • A. Bartoszek-Pączkowska
  • J. Namieśnik

  - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - Year 2013

  Isoprostanes are stable products of arachidonic acid peroxidation and are regarded as the most reliable markers of oxidative stress in vivo. Here we describe the LC-MS/MS procedure enabling simultaneous determination of four regioisomers (8-iso prostaglandin F2α, 8-iso-15(R)-prostaglandin F2α, 11β-prostaglandin F2α, 15(R)-prostaglandin F2α) in plasma samples collected from mice. The four plasma isoprostanes are determined by LC–ESI-MS/MS...

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