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1,3,4-Thiadiazole-based diamides: Synthesis and complexation properties

Abstract

Aromatic diamides, derivative of 2,6-pyridinedicarboxylic acid and isophthalic acid, bearing 1,3,4-thiadiazole residue were prepared with satisfactory yields in conventional procedures and microwave stimulated reactions. X-ray structure of N,N-bis (1,3,4-thiadiazol-2-yl)-2,6-pyridinedicarboxamide (2) DMSO solvate (2DMSO) was described. Selective zinc(II), lanthanum(III), terbium(III) and L-tyrosine recognition was found for N,N-bis(1,3,4-thiadiazol-2-yl)-2,6-pyridinedicarboxamide in DMSO and its mixture with water. The IDA (Indicator Displacement Assay) system for metal cations sensing was proposed. The binding properties of 2 were compared with newly synthesized N,N-bis(1,3,4-thiadiazol-2-yl)-1,3-benzenedicarboxamide 1.

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Keywords

Details

Category:
Articles
Type:
artykuł w czasopiśmie wyróżnionym w JCR
Published in:
JOURNAL OF MOLECULAR STRUCTURE no. 1146, pages 713 - 722,
ISSN: 0022-2860
Language:
English
Publication year:
2017
Bibliographic description:
Łukasik N., Luboch E., Chojnacki J., Wagner-Wysiecka E.: 1,3,4-Thiadiazole-based diamides: Synthesis and complexation properties// JOURNAL OF MOLECULAR STRUCTURE. -Vol. 1146, (2017), s.713-722
DOI:
Digital Object Identifier (open in new tab) 10.1016/j.molstruc.2017.06.057
Verified by:
Gdańsk University of Technology

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