ANALYSIS OF THE p53 PROTEIN GENE EXPRESSION MODEL

Agnieszka Bartłomiejczyk; Marek Bodnar; Monika Piotrowska

ANALYSIS OF THE p53 PROTEIN GENE EXPRESSION MODEL

Abstract

We study the asymptotic behaviour of the solutions of the p53-Mdm2 model proposed by Monk (2003). The p53 gene is crucial for cellular inhibition of the angiogenesis process, while Mdm2 is a negative regulator of the p53 tumor-suppressor. We investigate the stability of the positive steady state and perform some numerical experiments.

Authors (3)

Agnieszka Bartłomiejczyk dr
Marek Bodnar dr hab.
- Wydział Matematyki, Informatyki i Mechaniki, UW Zakład Biomatematyki i Teorii Gier
Monika Piotrowska dr
- Wydział Matematyki, Informatyki i Mechaniki, UW Zakład Biomatematyki i Teorii Gier

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Keywords

PROTEIN GENE EXPRESSION

Details

Category:: Conference activity
Type:: publikacja w wydawnictwie zbiorowym recenzowanym (także w materiałach konferencyjnych)
Title of issue:: Proceedings of the Twenty-Fist National Conference on Applications of Mathematics in Biology and Medicine strony 21 - 26
Language:: English
Publication year:: 2015
Bibliographic description:: Bartłomiejczyk A., Bodnar, M., Piotrowska, M.: ANALYSIS OF THE p53 PROTEIN GENE EXPRESSION MODEL// Proceedings of the Twenty-Fist National Conference on Applications of Mathematics in Biology and Medicine/ : , 2015, s.21-26
Verified by:: Gdańsk University of Technology