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Analytical aspects of model compounds toxicity assessment using MTT and Microtox bioanalytica assays
Abstract
More and more increased intensity of anthropopressure processes can be observed, among other things, in the release of great quantities of synthetic substances into the environment, including the Endocrine Disrupting Compounds. The effects of the above-mentioned human impact on the environment not only can be noticed in the homeostasis disturbance in ecosystems, but they are also visible with respect to human. The high incidence rate of cancer and other civilization diseases has become a serious social problem. Therefore, all attempts to broaden the knowledge about the relations and mechanisms triggering the development of relevant diseases are justified. The goal of the conducted research was to use bioanalytic methods to evaluate cytotoxicity and acute toxicity of the selected EDCs which cause serious food contamination (bisphenol A, 4-nonynphenol, 4-t-octylphenol, diethylstilbestrol, bisphenol A diglycidyl ether and its derivatives and phthalates) with MTT cel viability assay and Microtox® assay.
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- Category:
- Conference activity
- Type:
- publikacja w wydawnictwie zbiorowym recenzowanym (także w materiałach konferencyjnych)
- Title of issue:
- Proceeding of the 11th International Students Conference : "Modern Analytical Chemistry" strony 150 - 156
- Language:
- English
- Publication year:
- 2015
- Bibliographic description:
- Kudłak B., Mazerska Z., Namieśnik J., Owczarek K.: Analytical aspects of model compounds toxicity assessment using MTT and Microtox bioanalytica assays// Proceeding of the 11th International Students Conference : "Modern Analytical Chemistry"/ ed. Karel Nesmerak Praga, Czechy: , 2015, s.150-156
- Verified by:
- Gdańsk University of Technology
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