Clinical studies of detecting COVID-19 from exhaled breath with electronic nose

Andrzej Kwiatkowski; Sebastian Borys; Katarzyna Sikorska; Katarzyna Drozdowska; Janusz Smulko

doi:10.1038/s41598-022-20534-8

Clinical studies of detecting COVID-19 from exhaled breath with electronic nose

Abstract

The COVID‑19 pandemic has attracted numerous research studies because of its impact on society and the economy. The pandemic has led to progress in the development of diagnostic methods, utilizing the polymerase chain reaction (PCR) as the gold standard for coronavirus SARS‑CoV‑2 detection. Numerous tests can be used at home within 15 min or so but of with lower accuracy than PCR. There is still a need for point‑of‑care tests available for mass daily screening of large crowds in airports, schools, and stadiums. The same problem exists with fast and continuous monitoring of patients during their medical treatment. The rapid methods can use exhaled breath analysis which is non‑invasive and delivers the result quite fast. Electronic nose can detect a cocktail of volatile organic com‑pounds (VOCs) induced by virus infection and disturbed metabolism in the human body. In our exploratory studies, we present the results of COVID‑19 detection in a local hospital by applying the developed electronic setup utilising commercial VOC gas sensors. We consider the technical problems noticed during the reported studies and affecting the detection results. We believe that our studies help to advance the proposed technique to limit the spread of COVID‑19 and similar viral infections.

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Authors (5)

Andrzej Kwiatkowski dr inż.
Sebastian Borys
Katarzyna Sikorska
- Gdański Uniwersytem Medyczny
Katarzyna Drozdowska mgr inż.
Janusz Smulko prof. dr hab. inż.

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Category:

Articles

Type:

artykuły w czasopismach

Published in:

Scientific Reports no. 12,
ISSN: 2045-2322

Language:

English

Publication year:

2022

Bibliographic description:

Kwiatkowski A., Borys S., Sikorska K., Drozdowska K., Smulko J.: Clinical studies of detecting COVID-19 from exhaled breath with electronic nose// Scientific Reports -Vol. 12,iss. 1 (2022), s.15990-

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