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Convenient and efficient synthesis of functionalized unsymmetrical alkynyl sulfides

Abstract

We developed a simple and efficient method for the synthesis of functionalized unsymmetrical alkynyl sulfides under mild conditions in good yields. The designed method is based on the reaction of 5,5-dimethyl-2-thioxo-1,3,2-dioxaphosphorinan-2-disulfanyl derivatives with lithium acetylides. The developed method allows the preparation of unsymmetrical alkynyl sulfides bearing additional hydroxyl, carboxyl, or amino functionalities.

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DOI:
Digital Object Identifier (open in new tab) 10.1039/C6RA19440K
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Copyright (2016 The Royal Society of Chemistry)

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Category:
Articles
Type:
artykuł w czasopiśmie wyróżnionym w JCR
Published in:
RSC Advances no. 6, edition 107, pages 105449 - 105453,
ISSN: 2046-2069
Language:
English
Publication year:
2016
Bibliographic description:
Doroszuk J., Musiejuk M., Witt D., Demkowicz S., Rachoń J.: Convenient and efficient synthesis of functionalized unsymmetrical alkynyl sulfides// RSC Advances. -Vol. 6, iss. 107 (2016), s.105449-105453
DOI:
Digital Object Identifier (open in new tab) 10.1039/c6ra19440k
Verified by:
Gdańsk University of Technology

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