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Abstract
The effect of a natural filler (diatomaceous earth [DE], a promising drug-delivery agent) and its content was investigated on the performance of a model glass-ionomer cement (GIC). Three sample series, differing in DE content (0, 2.5 and 5 wt%), were prepared using a commercial GIC as a matrix (3M Ketac Molar Easymix). The resultant surface microhardness and roughness, wear performance, and compressive strength of the samples were measured after the samples had been stored in deionized water at 37°C for a fixed time. Moreover, the film thickness was tested for the freshly mixed samples. The numerical data was subjected to statistical analysis, in order to test the null hypotheses of the equality of the measured properties between the reference and the DE-modified samples. According to the results, diatomaceous earth particles are uniformly distributed in the GIC matrix, and the cavities of frustules tend to be filled with the GIC. This translates into the observed performance of the DE-loaded GIC. Compared with the reference material (0 wt% DE), the surface microhardness (2.5 wt% DE, p = 0.014; 5 wt% DE, p = 0.005) and roughness (e.g. Ra; 2.5 wt% DE, p = 0.003; 5 wt% DE, p < 0.001) are increased. No effect on the wear performance (p = 0.530 and 0.256, respectively) or compressive strength (p = 0.514) was noticed in the case of DE partially substituting the glass phase. Based on the study results, it is evidenced that diatom frustules are a suitable filler for application in conventional glass-ionomer cements as the glass-substituting drug-loaded carrier. Notably, however, the surface finish method of the DE-filled materials needs development.
Citations
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Authors (6)
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Magdalena Łępicka dr inż
- Institute of Mechanical Engineering, Faculty of Mechanical Engineering, Bialystok University of Technolog
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Magdalena Rodziewicz
- Bialystok University of Technology
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Michał Kawalec dr inż.
- Institute of Mechanical Engineering, Faculty of Mechanical Engineering, Bialystok University of Technolog
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Klaudia Nowicka
- Institute of Mechanical Engineering, Faculty of Mechanical Engineering, Bialystok University of Technolog
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Jan Krzysztof Kurzydłowski
- Institute of Mechanical Engineering, Faculty of Mechanical Engineering, Bialystok University of Technolog
Cite as
Full text
- Publication version
- Accepted or Published Version
- DOI:
- Digital Object Identifier (open in new tab) 10.1016/j.jmbbm.2022.105324
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Details
- Category:
- Articles
- Type:
- artykuły w czasopismach
- Published in:
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Journal of the Mechanical Behavior of Biomedical Materials
no. 133,
ISSN: 1751-6161 - Language:
- English
- Publication year:
- 2022
- Bibliographic description:
- Łępicka M., Rodziewicz M., Kawalec M., Nowicka K., Tsybrii Y., Kurzydłowski J. K.: Diatomaceous earth as a drug-loaded carrier in a glass-ionomer cement// Journal of the Mechanical Behavior of Biomedical Materials -Vol. 133, (2022), s.105324-
- DOI:
- Digital Object Identifier (open in new tab) 10.1016/j.jmbbm.2022.105324
- Sources of funding:
-
- Free publication
- Verified by:
- Gdańsk University of Technology
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