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Endocrine Disrupting Compounds – Problems and Challenges

Abstract

In this chapter, information about some of the estrogenic compounds and their environmental fate and biological influence can be found. Special attention is paid to the review of the analytical approaches used at the stages of detection and determination of Endocrine Disrupting Compounds (EDCs) in the environmental samples. Also, a brief characterization of both cellular and non-cellular bioassays is presented. The discovery of micropollutants occurring in the environment resulted in new methodologies being put into the analytical practice. These methodologies are developed in two different directions. The first is based on methodological solutions designed to detect, identify, and determine xenobiotics that occur in various environmental samples. For this purpose, instrumental methods such as gas and liquid chromatography with mass spectrometry detection are usually used. The second approach is to put into the analytical practice the new bioanalytical methodologies. These methodologies allow the estimation of the sample endocrine potential, but they do not provide the information about which of the sample ingredient is responsible for causing the toxic effect. These results can be the basis for estimating the endocrine potential of the environment exhibited by certain species. Moreover, bioanalytical techniques may be supplementary to the techniques of quantitative and qualitative determination of EDCs.

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Details

Category:
Monographic publication
Type:
rozdział, artykuł w książce - dziele zbiorowym /podręczniku w języku o zasięgu międzynarodowym
Title of issue:
W : Emerging Pollutants in the Environment - Current and Further Implications strony 169 - 201
Language:
English
Publication year:
2015
Bibliographic description:
Kudłak B., Szczepańska N., Owczarek K., Mazerska Z., Namieśnik J.: Endocrine Disrupting Compounds – Problems and Challenges// W : Emerging Pollutants in the Environment - Current and Further Implications/ ed. Marcelo L. Larramendy and Sonia Soloneski : InTech Open, 2015, s.169-201
DOI:
Digital Object Identifier (open in new tab) 10.5772/60410
Verified by:
Gdańsk University of Technology

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