Search
Abstract
Lanosterol is the crucial intermediate in ergosterol biosynthesis in fungi. A number of derivatives of natural or synthetic origin of these sterols are portrayed in this review. For the synthetic derivatives, strategies of their syntheses are presented. Biological activities of lanosterol and ergosterol derivatives include antimicrobial, especially antifungal action, anticancer and antiviral effects but also anti-inflammatory and anti-allergic potential. The most promising seems to be the anticancer potential of peroxides, epoxides, and keto- derivatives of both sterols.
Citations
-
0
CrossRef
-
0
Web of Science
-
0
Scopus
Cite as
Full text
full text is not available in portal
Keywords
Details
- Category:
- Articles
- Type:
- artykuły w czasopismach dostępnych w wersji elektronicznej [także online]
- Published in:
-
CHEMMEDCHEM
pages 1 - 25,
ISSN: 1860-7179 - Language:
- English
- Publication year:
- 2025
- Bibliographic description:
- Stefaniak-Skorupa J., Milewska M., Ergosterol and Lanosterol Derivatives: Synthesis and Possible Biomedical Applications, CHEMMEDCHEM, 2025,10.1002/cmdc.202400948
- DOI:
- Digital Object Identifier (open in new tab) 10.1002/cmdc.202400948
- Sources of funding:
-
- Free publication
- Verified by:
- Gdańsk University of Technology
seen 0 times
Recommended for you
Anticancer and antimicrobial properties of novel η6-p-cymene ruthenium(ii) complexes containing a N,S-type ligand, their structural and theoretical characterization
- E. Namiecińska,
- B. Sadowska,
- M. Więckowska-Szakiel
- + 4 authors
2019
Novel 2-(2-alkylthiobenzenesulfonyl)-3-(phenylprop-2-ynylideneamino)guanidine derivatives as potent anticancer agents – Synthesis, molecular structure, QSAR studies and metabolic stability
- A. Pogorzelska,
- J. Sławiński,
- B. Żołnowska
- + 6 authors
2017
Novel N-(aryl/heteroaryl)-2-chlorobenzenesulfonamide derivatives: synthesis and anticancer activity evaluation
- A. Bułakowska,
- J. Sławiński,
- K. Siedlecka-Kroplewska
- + 3 authors
2020