MutL protein as a constituent of vsp, ner and mmr repair systems - Publication - MOST Wiedzy

Search

MutL protein as a constituent of vsp, ner and mmr repair systems

Abstract

MutS and MutL proteins are renowned mostly for their functions in well-characterized, post-DNA replication mis- match repair system (MMR). However, there is growing evidence that MMR system is not the only field of action for these pro- teins. Moreover, the participation in MMR does not even have to be their primary function. There are some reports indicat- ing involvement of MutL in BER, NER and VSP (very short patch repair). MutL protein interacts with MMR proteins such as MutS, MutH, UvrD, ExoX as well as with proteins which do not belong to MMR proteins family: ß and subunits of DNA polymerase III and RecA protein. The ability of MutL to interact structurally and functionally with a number of different proteins makes this protein a perfect candidate for the master regulator coupling MMR system with other DNA repair mechanisms

Cite as

Full text

full text is not available in portal

Keywords

Details

Category:
Monographic publication
Type:
rozdział, artykuł w książce - dziele zbiorowym /podręczniku w języku o zasięgu międzynarodowym
Title of issue:
PhD interdisciplinary Journal. No. 2 strony 9 - 15
Language:
English
Publication year:
2013
Bibliographic description:
Banasik M.: MutL protein as a constituent of vsp, ner and mmr repair systems// PhD interdisciplinary Journal. No. 2/ : Politechnika Gdańska, 2013, s.9-15
Verified by:
Gdańsk University of Technology

seen 28 times

Recommended for you

Meta Tags