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New method to monitor changes in the subarachnoid width and pial artery pulsation for physiological and clinical research
Abstract
There are several medical conditions associated with brain oedema such as traumatic brain injury, intoxication or tumors. Brain edema and related brain parenchyma expansion may lead to compression and subsequent injury of several brain structures. So far, the only method enabling detection and monitoring of the progress a cerebral oedema in a patient, has been monitoring of intracranial pressure (ICP) with a pressure probe inserted into the skull through an opening in the skull bones (trepanation), a method as informative as invasive. Computed tomography (CT) and Magnetic Resonance Imaging (MRI), however accurate and informative does not allow for continues bedside monitoring. The advent of transcranial Doppler technology has opened a new era in human research. Therefore, it is important to develop methods allowing to non-invasively, instantly and continuously monitor changes in brain microcirculation and intracranial compartment. The main disadvantage of transcranial Doppler technology is that the measurement is performed in large cerebral arteries, and reflects cerebral blood flow velocity, while the regulation of cerebral blood flow takes place in small arterioles.
Authors (3)
-
Andrzej Frydrychowski
- . .
-
Paweł Winklewski
- . .
Cite as
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Keywords
Details
- Category:
- Other
- Type:
- supllement, wydanie specjalne, dodatek
- Published in:
-
JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
no. 65,
pages 79 - 79,
ISSN: 0867-5910 - Language:
- English
- Publication year:
- 2014
- Verified by:
- Gdańsk University of Technology
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