Search results for: GENE EXPRESSION REGULATION

• GENE EXPRESSION

  Journals

  ISSN: 1052-2166

• The role of TGF superfamily gene expression in the regulation of folliculogenesis and oogenesis in mammals: a review

  Publication

  • H. Piotrowska
  • B. Kempisty
  • P. Sosinska
  • S. Ciesiolka
  • D. Bukowska
  • P. Antosik
  • M. Rybska
  • K. Brussow
  • M. Nowicki
  • M. Zabel

  - VETERINARNI MEDICINA - Year 2013

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• GENE EXPRESSION PATTERNS

  Journals

  ISSN: 1567-133X , eISSN: 1872-7298

• Analysis of a gene expression model

  Publication

  • A. Bartłomiejczyk
  • M. Bodnar

  - Year 2017

  We study a mathematical model of gene transcription and protein synthesis with negative feedback. We consider a system of equations taking into account the number of active binding sites, the way in which dimers bind to DNA and time delay in translation process. For a simplified model that consist of three ordinary differential equations with time delay we derive conditions for stability of the positive steady state and for the...

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• Gene Regulation and Systems Biology

  Journals

  ISSN: 1177-6250

• CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

  Journals

  ISSN: 1045-4403 , eISSN: 2162-6502

• Modelling gene expression of a self-regulating protein

  Publication

  • A. Bartłomiejczyk
  • M. Bodnar

  - Year 2014

  We analyze a model of gene transcription and protein synthesis. We take into account the number of sites on the protein’s promoter at which the protein’s dimers can bind blocking transcription of protein mRNA.

• ANALYSIS OF THE p53 PROTEIN GENE EXPRESSION MODEL

  Publication

  • A. Bartłomiejczyk
  • M. Bodnar
  • M. Piotrowska

  - Year 2015

  We study the asymptotic behaviour of the solutions of the p53-Mdm2 model proposed by Monk (2003). The p53 gene is crucial for cellular inhibition of the angiogenesis process, while Mdm2 is a negative regulator of the p53 tumor-suppressor. We investigate the stability of the positive steady state and perform some numerical experiments.

• Hopf bifurcation in time‐delayed gene expression model with dimers

  Publication

  • A. Bartłomiejczyk
  • M. Bodnar

  - MATHEMATICAL METHODS IN THE APPLIED SCIENCES - Year 2023

  We study a mathematical model of gene transcription and protein synthesis with negative feedback. We consider a system of equations taking into account the formation of dimers (i.e., complex formed by two protein monomers), the way in which dimers bind to DNA and time delay in translation process. For the model consisting of three ordinary differential equations with time delay, we derive conditions for stability of the positive...

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• Delay induced oscillations in gene expression of Hes1 protein model

  Publication

  • M. Bodnar
  • A. Bartłomiejczyk

  - Year 2010

  W pracy został omówiony model produkcji białka Hes1. Stężenie Hes1 jest kontrolowane przez ujemne sprzężenie zwrotne wbudowane w białko i jego mRNA. Przeprowadzona analiza potwierdziła znane wyniki numeryczne, że oscylacje wywołane są przez opóźnienie. Pokazaliśmy również, że jeśli współczynnik Hilla jest większy niż 1, to istnieje krytyczna wartość opóźnienia, dla której ma miejsce bifurkacja Hopfa i pojawiają się rozwiązania...