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Search results for: Melan A
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The role of melanin pigment in melanoma
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Transplantable Melanomas in Hamsters and Gerbils as Models for Human Melanoma. Sensitization in Melanoma Radiotherapy—From Animal Models to Clinical Trials
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Antitumor Effects of Vitamin D Analogs on Hamster and Mouse Melanoma Cell Lines in Relation to Melanin Pigmentation
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Targeting melanocortin receptor type 1 with small peptides
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De syntaxi Filipa Melanchtona podręcznikiem do praktycznej stylistyki łacińskiej
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L-tyrosine and L-dihydroxyphenylalanine as hormone-like regulators of melanocyte functions
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Adaptacja inwazyjnych gatunków ichtiofauny w wodach Zatoki Gdańskiej na przykładzie Neogobius melanostomus
PublicationBabka bycza Neogobius melanostomus (Pallas, 1811) jest rybą pochodzącą z rejonów Morza Czarnego, Morza Kaspijskiego i Morza Azowskiego [23]. Jednak od kilkunastu lat zasiedla nowe rejony geograficzne m.in. Zatokę Gdańską, w której w strefie przybrzeżnej stała się rybą dominującą. Sprzyjające dla babki byczej warunki środowiska w polskich wodach t.j.: brak naturalnych wrogów i dostatek pokarmu sprawiły, że gatunek ten zaczął się...
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Laboratory Bioassay of Selected Entomopathogenic Nematodes as Mortality Factors of Oulema melanopus (Coleoptera: Chrysomelidae)
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Vitamin D signaling and melanoma: role of vitamin D and its receptors in melanoma progression and management
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Effect of Melanin on the Stability of Casein Films Exposed to Artificially Accelerated UV Aging
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Proteomic profile of melanoma cell‐derived small extracellular vesicles in patients’ plasma: a potential correlate of melanoma progression
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Mangiferin Affects Melanin Synthesis by an Influence on Tyrosinase: Inhibition, Mechanism of Action and Molecular Docking Studies
PublicationMangiferin is a strong antioxidant that presents a wide range of biological activities. The aim of this study was to evaluate, for the first time, the influence of mangiferin on tyrosinase, an enzyme responsible for melanin synthesis and the unwanted browning process of food. The research included both the kinetics and molecular interactions between tyrosinase and mangiferin. The research proved that mangiferin inhibits tyrosinase...
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Intelligent system supporting diagnosis of malignant melanoma
PublicationMalignant melanomas are the most deadly type of skin cancers. Early diagnosis is a key for successful treatment and survival. The paper presents the system for supporting the process of diagnosis of skin lesions in order to detect a malignant melanoma. The paper describes the development process of an intel-ligent system purposed for the diagnosis of malignant melanoma. Presented sys-tem can be used as a decision support system...
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Foliar Application of Entomopathogenic Nematodes against Cereal Leaf Beetle Oulema melanopus L. (Coleoptera: Chrysomelidae) on Wheat
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Bifunctional Opioid/Melanocortin Peptidomimetics for Use in Neuropathic Pain: Variation in the Type and Length of the Linker Connecting the Two Pharmacophores
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Common variants of DNA repair genes and malignant melanoma
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New vitamin D analogs as potential therapeutics in melanoma
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XPD Common Variants and their Association with Melanoma and Breast Cancer Risk
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Proteomic Analysis of Proton Beam Irradiated Human Melanoma Cells
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Liquid Biopsy in Melanoma: Significance in Diagnostics, Prediction and Treatment Monitoring
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The assessment of students’ knowledge regarding melanoma and sun-protection habits
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Effect of polyphenols from Aronia melanocarpa on the total oxidative and antioxidative bone status of cadmium-exposed rats
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MC1R common variants, CDKN2A and their association with melanoma and breast cancer risk
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ELECTROCHEMOTHERAPY COMBINED WITH STANDARD AND CO2 LASER SURGERIES IN CANINE ORAL MELANOMA
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On the role of classical and novel forms of vitamin D in melanoma progression and management
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Protective Effect of Aronia Melanocarpa Polyphenols on Cadmium Accumulation in the Body: A Study in a Rat Model of Human Exposure to this Metal
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Melanoma skin cancer detection using mask-RCNN with modified GRU model
PublicationIntroduction: Melanoma Skin Cancer (MSC) is a type of cancer in the human body; therefore, early disease diagnosis is essential for reducing the mortality rate. However, dermoscopic image analysis poses challenges due to factors such as color illumination, light reflections, and the varying sizes and shapes of lesions. To overcome these challenges, an automated framework is proposed in this manuscript. Methods: Initially, dermoscopic...
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Fluorescence Imaging Using Methylene Blue Sentinel Lymph Node Biopsy in Melanoma
PublicationIntroduction: Fluorescence imaging of sentinel node biopsy in melanoma is a novel method. Both indocyanine green (ICG) and methylene blue (MB) have fl uorescent properties. The aim of this study was to present, for the fi rst time in a clinical series of patients, the possible usage of MB as a fl uorescent dye for sentinel node biopsy during surgery for melanoma. Material and methods: Twenty patients with...
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Cytotoxic effect on human melanoma cell lines and tyrosinase inhibition of Hottonia palustris
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Novel therapeutic compound acridine–retrotuftsin action on biological forms of melanoma and neuroblastoma
PublicationPURPOSE: As a continuation of our search for anticancer agents, we have synthesized a new acridine-retrotuftsin analog HClx9-[Arg(NO2)-Pro-Lys-Thr-OCH3]-1-nitroacridine (named ART) and have evaluated its activity against melanoma and neuroblastoma lines. Both tumors develop from cells (melanocytes, neurons) of neuroectodermal origin, and both are tumors with high heterogeneity and unsatisfactory susceptibility to chemotherapies....
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Graphene-encapsulated iron nanoparticles as a non-viral vector for gene delivery into melanoma cells
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An Insight into the Proteome of Uveal Melanoma-Derived Ectosomes Reveals the Presence of Potentially Useful Biomarkers
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Similarities and Differences in the Protein Composition of Cutaneous Melanoma Cells and Their Exosomes Identified by Mass Spectrometry
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Anticancer properties of ester derivatives of betulin in human metastatic melanoma cells (Me-45)
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The effects of p53 gene inactivation on mutant proteome expression in a human melanoma cell model
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Apoptosis induction in C32 human melanoma cells by Jasione montana and its main phytoconstituents
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The Mechanism of the Osteoprotective Action of a Polyphenol-Rich Aronia melanocarpa Extract during Chronic Exposure to Cadmium is Mediated by the Oxidative Defense System
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Concomitant consumption of Aronia melanocarpa aqueous extract and low cadmium doses improve serum and bone antioxidative status in a rat model
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Estimation of the Chelating Ability of an Extract from Aronia melanocarpa L. Berries and Its Main Polyphenolic Ingredients Towards Ions of Zinc and Copper
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Polymer-free cubosomes for simultaneous bioimaging and photodynamic action of photosensitizers in melanoma skin cancer cells
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Using Flavonoid Substitution Status to Predict Anticancer Effects in Human Melanoma Cancers: An In Vitro Study
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Protective impact of extract from Aronia melanocarpa berries against low-level exposure to cadmium-induced liver damage: a study in a rat model
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Mass Spectrometry-Based Proteomic Characterization of Cutaneous Melanoma Ectosomes Reveals the Presence of Cancer-Related Molecules
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In Vitro Anticancer Potential of Jasione montana and Its Main Components against Human Amelanotic Melanoma Cells
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DEEP CONVOLUTIONAL NEURAL NETWORKS AS A DECISION SUPPORT TOOL IN MEDICAL PROBLEMS – MALIGNANT MELANOMA CASE STUDY
PublicationThe paper presents utilization of one of the latest tool from the group of Machine learning techniques, namely Deep Convolutional Neural Networks (CNN), in process of decision making in selected medical problems. After the survey of the most successful applications of CNN in solving medical problems, the paper focuses on the very difficult problem of automatic analyses of the skin lesions. The authors propose the CNN structure...
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Protective effect of Aronia melanocarpa polyphenols against cadmium-induced disorders in bone metabolism: A study in a rat model of lifetime human exposure to this heavy metal
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Law regulation in Poland related to biofuels
PublicationThe situation in the area of using biofuels in transport mostly the law aspects was presented and discussed. In Poland there are various legal issues with biofuel production, examination and use. These include among the others: quality inspection, production costs and market prices of biofuels, forms of public and legal service for biofuel producers or programs of biofuels promotion. In order to popularise biofuels it is significant...
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Pilot- scale plant for material recycling of whole waste tires
PublicationContinously growing demad for all kinds of vehicles and general tendency to regular exchange of tires are causing growth of scrap tires which need management. A risings of large quantities of used rubber products, especially used tires has been increasing every year in Poland, in 2006 it was 160 thousand. The waste management and recycling of used tires become a major environmental problem. It is worth noticing that tires which...
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Bioactive core material for porous load-bearing implants
PublicationSo far state of knowledge on biodegradable materials is reviewed. Among a variety of investigated materials, those composed of polymers and ceramics may be considered as only candidates for a core material in porous titanium alloy. The collagen and chitosan among natural polymers, polyhydroxy acids among synthetic polymers, and hydroxyapatite and tricalcium phosphate among ceramics are proposed for further research. Three essential...
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Low prevalence of CDKN2A/ARF mutations among early-onset cancers of breast, pancreas and malignant melanoma in Poland
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