Search results for: GENTIANA

• Silver nanoparticles induce premutagenic DNA oxidation that can be prevented by phytochemicals from Gentiana asclepiadea

  Publication

  • A. HUDECOVá
  • B. Kusznierewicz
  • E. RUNDéN-PRAN
  • Z. MAGDOLENOVá
  • K. HAĄPLOVá
  • A. Rinna
  • L. M. Fjellsbø
  • M. Kruszewski
  • A. Lankoff
  • W. J. Sandberg... and 9 others

  - MUTAGENESIS - Year 2012

  Among nanomaterials, silver nanoparticles (AgNPs) have the broadest and most commercial applications due to their antibacterial properties, highlighting the need for exploring their potential toxicity and underlying mechanisms of action. Our main aim was to investigate whether AgNPs exert toxicity by inducing oxidative damage to DNA in human kidney HEK 293 cells. In addition, we tested whether this damage could be counteracted...

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• Gentiana asclepiadea exerts antioxidant activity and enhances DNA repair of hydrogen peroxide- and silver nanoparticles-induced DNA damage

  Publication

  • A. Hudecova
  • B. Kusznierewicz
  • K. Hasplova
  • A. Huk
  • Z. Magdolenova
  • E. Miadokova
  • E. Galova
  • M. Dusinska

  - FOOD AND CHEMICAL TOXICOLOGY - Year 2012

  Exposure to high levels of different environmental pollutants is known to be associated with induction of DNA damage in humans. Thus DNA repair is of great importance in preventing mutations and contributes crucially to the prevention of cancer. In our study we have focused on quantitative analysis of Gentiana asclepiadea aqueous or methanolic extracts obtained from flower and haulm, their antioxidant potency in ABTS post-column...

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